ACTIFED vs BENZAMYCIN

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 7, 2026·How we rate

Possible drug interaction. ACTIFED and BENZAMYCIN are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ACTIFED	BENZAMYCIN
Rating	72/100	74/100
Pharmacy pays	~$8.29 /30	$0.05 /g
Type	RX	RX
Active ingredient	PSEUDOEPHEDRINE HYDROCHLORIDE AND TRIPROLIDINE HYDROCHLORIDE	BENZOYL PEROXIDE AND ERYTHROMYCIN
Manufacturer	Glaxosmithkline	Valeant Pharm Intl
Dosage forms	Tablet	Kit
Drug class	—	—
Boxed warning	None	None
Half-life	roughly 3 to 16 hours — the label does not give one number, because the elimination half-life depends on urine pH: about 3 to 6 hours when urine pH is 5 (acidic), and about 9 to 16 hours when urine pH is 8 (alkaline)	—

actifed benzamycin

Rating

72/100

74/100

Pharmacy pays

~$8.29 /30

$0.05 /g

Type

Active ingredient

PSEUDOEPHEDRINE HYDROCHLORIDE AND TRIPROLIDINE HYDROCHLORIDE

BENZOYL PEROXIDE AND ERYTHROMYCIN

Manufacturer

Glaxosmithkline

Valeant Pharm Intl

Dosage forms

Tablet

Kit

Drug class

—

Boxed warning

None

Half-life

roughly 3 to 16 hours — the label does not give one number, because the elimination half-life depends on urine pH: about 3 to 6 hours when urine pH is 5 (acidic), and about 9 to 16 hours when urine pH is 8 (alkaline)

—

Frequently asked questions

Which is better-rated, Actifed or Benzamycin?

By our independent rating, Benzamycin scores higher — 3.7 vs 3.6 out of 5 for Actifed. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Actifed and Benzamycin?

Actifed contains Pseudoephedrine Hydrochloride and Triprolidine Hydrochloride, while Benzamycin contains Benzoyl Peroxide and Erythromycin — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.