ACTIDIL vs PROGRAF

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Possible drug interaction. ACTIDIL and PROGRAF are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ACTIDIL	PROGRAF
Rating	70/100	72/100
Pharmacy pays	$0.39 /mL	$0.65 /g
Type	RX	RX
Active ingredient	TRIPROLIDINE HYDROCHLORIDE	TACROLIMUS
Manufacturer	Glaxosmithkline	Astellas
Dosage forms	Syrup, Tablet	Capsule, Powder, Injectable
Drug class	—	Calcineurin Inhibitor Immunosuppressant
Boxed warning	None	Boxed warning
Treats	Allergic Conjunctivitis, Atopic Dermatitis, Rhinitis	Atopic Dermatitis, Graft Vs Host Disease

actidil prograf

Rating

70/100

72/100

Pharmacy pays

$0.39 /mL

$0.65 /g

Type

Active ingredient

TRIPROLIDINE HYDROCHLORIDE

TACROLIMUS

Manufacturer

Glaxosmithkline

Astellas

Dosage forms

Syrup, Tablet

Capsule, Powder, Injectable

Drug class

—

Calcineurin Inhibitor Immunosuppressant

Boxed warning

None

Boxed warning

Treats

Allergic Conjunctivitis, Atopic Dermatitis, Rhinitis

Atopic Dermatitis, Graft Vs Host Disease

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Frequently asked questions

Which is better-rated, Actidil or Prograf?

By our independent rating, Prograf scores higher — 3.6 vs 3.5 out of 5 for Actidil. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Actidil and Prograf?

Actidil contains Triprolidine Hydrochloride, while Prograf contains Tacrolimus — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.