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ACTICORT vs SERNIVO

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 20, 2026·How we rate

Possible drug interaction. ACTICORT and SERNIVO are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

New
72/100

Pharmacy pays

$0.15 /g

Type

RX
RX

Active ingredient

HYDROCORTISONE
BETAMETHASONE DIPROPIONATE

Dosage forms

Topical
Spray/Inhaler

Drug class

Corticosteroid
Corticosteroid

Boxed warning

None
None

Half-life

about 1.5 hours

Treats

Adrenal Insufficiency, Congenital Adrenal Hyperplasia, Ulcerative Colitis
Atopic Dermatitis, Facial Dermatoses, Foot Dermatoses

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Frequently asked questions

What is the difference between Acticort and Sernivo?

Acticort contains Hydrocortisone, while Sernivo contains Betamethasone Dipropionate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.