ACIPHEX vs PREVACID

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Possible drug interaction. ACIPHEX and PREVACID are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ACIPHEX	PREVACID
Rating	New	New
Pharmacy pays	—	~$5.10 /30
Type	RX	RX
Active ingredient	RABEPRAZOLE SODIUM	LANSOPRAZOLE
Manufacturer	Eisai Medcl Res	Takeda Pharms USA
Dosage forms	Tablet, delayed release	Capsule, delayed release
Drug class	Proton Pump Inhibitor	Proton Pump Inhibitor
Boxed warning	None	None
Half-life	—	about 1.5 hours (mean, ±1.0) in healthy adults — the label states the plasma elimination half-life is less than two hours
Treats	Duodenal Ulcer, Gastroesophageal Reflux, Heartburn	Duodenal Ulcer, Esophagitis, Gastroesophageal Reflux

aciphex prevacid

Rating

New

Pharmacy pays

—

~$5.10 /30

Type

Active ingredient

RABEPRAZOLE SODIUM

LANSOPRAZOLE

Manufacturer

Eisai Medcl Res

Takeda Pharms USA

Dosage forms

Tablet, delayed release

Capsule, delayed release

Drug class

Proton Pump Inhibitor

Boxed warning

None

Half-life

—

about 1.5 hours (mean, ±1.0) in healthy adults — the label states the plasma elimination half-life is less than two hours

Treats

Duodenal Ulcer, Gastroesophageal Reflux, Heartburn

Duodenal Ulcer, Esophagitis, Gastroesophageal Reflux

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Frequently asked questions

What is the difference between Aciphex and Prevacid?

Aciphex contains Rabeprazole Sodium, while Prevacid contains Lansoprazole — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.