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ACIPHEX vs PANTOPRAZOLE SODIUM

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Possible drug interaction. ACIPHEX and PANTOPRAZOLE SODIUM are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

New
New

Pharmacy pays

~$120.76 /30

Type

RX
RX

Active ingredient

RABEPRAZOLE SODIUM
PANTOPRAZOLE SODIUM

Dosage forms

Tablet, delayed release
Powder, delayed release, Injectable, Solution, Powder, Tablet, delayed release

Drug class

Proton Pump Inhibitor
Proton Pump Inhibitor

Boxed warning

None
None

Half-life

about 1 hour

Treats

Duodenal Ulcer, Gastroesophageal Reflux, Heartburn
Esophagitis, Gastroesophageal Reflux, Heartburn

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Frequently asked questions

What is the difference between Aciphex and Pantoprazole Sodium?

Aciphex contains Rabeprazole Sodium, while Pantoprazole Sodium contains Pantoprazole Sodium — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.