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ACCOLATE vs SINGULAIR

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 22, 2026·How we rate

Possible drug interaction. ACCOLATE and SINGULAIR are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

70/100
70/100

Pharmacy pays

~$19.34 /30

Type

RX
RX

Active ingredient

ZAFIRLUKAST
MONTELUKAST SODIUM

Dosage forms

Tablet
Powder, Tablet, chewable, Tablet

Drug class

Leukotriene Receptor Antagonist
Leukotriene Receptor Antagonist

Boxed warning

Half-life

about 2.7 to 5.5 hours

Treats

Asthma
Asthma, Perennial Allergic Rhinitis

Get accolatehigher-rated option

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Frequently asked questions

Which is better-rated, Accolate or Singulair?

Accolate and Singulair are tied at 3.5 out of 5 by our independent rating.

What is the difference between Accolate and Singulair?

Accolate contains Zafirlukast, while Singulair contains Montelukast Sodium — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.