ABREVA vs IBUPROFEN AND DIPHENHYDRAMINE CITRATE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Attribute	ABREVA	IBUPROFEN AND DIPHENHYDRAMINE CITRATE
Rating	72/100	New
Pharmacy pays	$6.64 /g	$0.04 /mL
Type	OTC	OTC
Active ingredient	DOCOSANOL	DIPHENHYDRAMINE CITRATE AND IBUPROFEN
Manufacturer	Haleon US Holdings	Pld Acquisitions LLC
Dosage forms	Topical	Tablet
Drug class	—	—
Boxed warning	None	None
Half-life	—	about 1.8 to 2.0 hours
Treats	Blister	—

abreva ibuprofen and diphenhydramine citrate

Rating

72/100

New

Pharmacy pays

$6.64 /g

$0.04 /mL

Type

OTC

Active ingredient

DOCOSANOL

DIPHENHYDRAMINE CITRATE AND IBUPROFEN

Manufacturer

Haleon US Holdings

Pld Acquisitions LLC

Dosage forms

Topical

Tablet

Drug class

—

Boxed warning

None

Half-life

—

about 1.8 to 2.0 hours

Treats

Blister

—

Get abrevahigher-rated option

Advertising disclosure: Some links are affiliate links. We may earn a commission at no extra cost to you. This never affects our independent ratings.

Where to buy

Buy over-the-counter from trusted retailers.

AmazonCheck price on Amazon

Frequently asked questions

What is the difference between Abreva and Ibuprofen and Diphenhydramine Citrate?

Abreva contains Docosanol, while Ibuprofen and Diphenhydramine Citrate contains Diphenhydramine Citrate and Ibuprofen — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.