ABREVA vs ADVIL PM

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 22, 2026·How we rate

Attribute	ABREVA	ADVIL PM
Rating	72/100	72/100
Pharmacy pays	$6.64 /g	$0.04 /mL
Type	OTC	OTC
Active ingredient	DOCOSANOL	DIPHENHYDRAMINE HYDROCHLORIDE AND IBUPROFEN
Manufacturer	Haleon US Holdings	Haleon US Holdings
Dosage forms	Topical	Capsule, Tablet
Drug class	—	—
Boxed warning	None	None
Half-life	—	about 1.8 to 2.0 hours
Treats	Blister	—

abreva advil pm

Rating

72/100

Pharmacy pays

$6.64 /g

$0.04 /mL

Type

OTC

Active ingredient

DOCOSANOL

DIPHENHYDRAMINE HYDROCHLORIDE AND IBUPROFEN

Manufacturer

Haleon US Holdings

Dosage forms

Topical

Capsule, Tablet

Drug class

—

Boxed warning

None

Half-life

—

about 1.8 to 2.0 hours

Treats

Blister

—

Get abrevahigher-rated option

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Frequently asked questions

Which is better-rated, Abreva or Advil Pm?

Abreva and Advil Pm are tied at 3.6 out of 5 by our independent rating.

What is the difference between Abreva and Advil Pm?

Abreva contains Docosanol, while Advil Pm contains Diphenhydramine Hydrochloride and Ibuprofen — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.