ABITREXATE vs FOLOTYN

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Possible drug interaction. ABITREXATE and FOLOTYN are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ABITREXATE	FOLOTYN
Rating	New	New
Pharmacy pays	~$4.92 /30	—
Type	RX	RX
Active ingredient	METHOTREXATE SODIUM	PRALATREXATE
Manufacturer	Abic	Acrotech Biopharma
Dosage forms	Injectable	Injectable
Drug class	Folate Analog Metabolic Inhibitor	Folate Analog Metabolic Inhibitor
Boxed warning	None	None
Half-life	about 3 to 10 hours	—
Treats	Juvenile Arthritis, Rheumatoid Arthritis, Breast Neoplasms	Peripheral T-Cell Lymphoma

abitrexate folotyn

Rating

New

Pharmacy pays

~$4.92 /30

—

Type

Active ingredient

METHOTREXATE SODIUM

PRALATREXATE

Manufacturer

Abic

Acrotech Biopharma

Dosage forms

Injectable

Drug class

Folate Analog Metabolic Inhibitor

Boxed warning

None

Half-life

about 3 to 10 hours

—

Treats

Juvenile Arthritis, Rheumatoid Arthritis, Breast Neoplasms

Peripheral T-Cell Lymphoma

Frequently asked questions

What is the difference between Abitrexate and Folotyn?

Abitrexate contains Methotrexate Sodium, while Folotyn contains Pralatrexate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.