ABIRATERONE ACETATE vs ESBRIET

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Possible drug interaction. ABIRATERONE ACETATE and ESBRIET are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ABIRATERONE ACETATE	ESBRIET
Rating	72/100	New
Pharmacy pays	~$25.50 /30	~$45.48 /30
Type	RX	RX
Active ingredient	ABIRATERONE ACETATE	PIRFENIDONE
Manufacturer	Hikma	Legacy Pharma
Dosage forms	Tablet	Tablet
Drug class	Cytochrome P450 17a1 Inhibitor	Pyridone
Boxed warning	None	None
Treats	Castration-Resistant Prostatic Neoplasms	Pulmonary Fibrosis

abiraterone acetate esbriet

Rating

72/100

New

Pharmacy pays

~$25.50 /30

~$45.48 /30

Type

Active ingredient

ABIRATERONE ACETATE

PIRFENIDONE

Manufacturer

Hikma

Legacy Pharma

Dosage forms

Tablet

Drug class

Cytochrome P450 17a1 Inhibitor

Pyridone

Boxed warning

None

Treats

Castration-Resistant Prostatic Neoplasms

Pulmonary Fibrosis

Frequently asked questions

Which is cheaper, Abiraterone Acetate or Esbriet?

Abiraterone Acetate costs pharmacies less to acquire — about $25.50 vs $45.48 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Abiraterone Acetate and Esbriet?

Abiraterone Acetate contains Abiraterone Acetate, while Esbriet contains Pirfenidone — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.