ABIRATERONE ACETATE vs DEMI-REGROTON

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Possible drug interaction. ABIRATERONE ACETATE and DEMI-REGROTON are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ABIRATERONE ACETATE	DEMI-REGROTON
Rating	72/100	70/100
Pharmacy pays	~$25.50 /30	~$2.67 /30
Type	RX	RX
Active ingredient	ABIRATERONE ACETATE	CHLORTHALIDONE AND RESERPINE
Manufacturer	Hikma	Sanofi Aventis US
Dosage forms	Tablet	Tablet
Drug class	Cytochrome P450 17a1 Inhibitor	—
Boxed warning	None	None
Half-life	—	about 40 hours on average (the label reports a mean half-life of 40 hours after a 50–200 mg dose, and an elimination half-life of 53 hours after 50 mg and 60 hours after 100 mg)
Treats	Castration-Resistant Prostatic Neoplasms	—

abiraterone acetate demi-regroton

Rating

72/100

70/100

Pharmacy pays

~$25.50 /30

~$2.67 /30

Type

Active ingredient

ABIRATERONE ACETATE

CHLORTHALIDONE AND RESERPINE

Manufacturer

Hikma

Sanofi Aventis US

Dosage forms

Tablet

Drug class

Cytochrome P450 17a1 Inhibitor

—

Boxed warning

None

Half-life

—

about 40 hours on average (the label reports a mean half-life of 40 hours after a 50–200 mg dose, and an elimination half-life of 53 hours after 50 mg and 60 hours after 100 mg)

Treats

Castration-Resistant Prostatic Neoplasms

—

Frequently asked questions

Which is better-rated, Abiraterone Acetate or Demi-Regroton?

By our independent rating, Abiraterone Acetate scores higher — 3.6 vs 3.5 out of 5 for Demi-Regroton. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Abiraterone Acetate or Demi-Regroton?

Demi-Regroton costs pharmacies less to acquire — about $2.67 vs $25.50 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Abiraterone Acetate and Demi-Regroton?

Abiraterone Acetate contains Abiraterone Acetate, while Demi-Regroton contains Chlorthalidone and Reserpine — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.