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8-HOUR BAYER vs NAPROXEN

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Possible drug interaction. 8-HOUR BAYER and NAPROXEN are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

New
72/100

Pharmacy pays

~$0.78 /30
$0.06 /mL

Type

RX
RX

Active ingredient

ASPIRIN
NAPROXEN

Manufacturer

Dosage forms

Tablet, extended release
Tablet

Drug class

Nonsteroidal Anti-Inflammatory Drug
Nonsteroidal Anti-Inflammatory Drug

Boxed warning

Half-life

about 20 minutes (the label also states 0.33 hours) for aspirin itself
about 12 to 17 hours

Treats

Rheumatoid Arthritis, Fever, Gout
Juvenile Arthritis, Rheumatoid Arthritis, Back Pain

Frequently asked questions

What is the difference between 8-Hour Bayer and Naproxen?

8-Hour Bayer contains Aspirin, while Naproxen contains Naproxen — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.