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8-HOUR BAYER vs JUNIOR STRENGTH ADVIL

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Rating

New
72/100

Pharmacy pays

~$0.78 /30
$0.04 /mL

Type

RX
OTC

Active ingredient

ASPIRIN
IBUPROFEN

Dosage forms

Tablet, extended release
Tablet, chewable, Tablet

Drug class

Nonsteroidal Anti-Inflammatory Drug
Nonsteroidal Anti-Inflammatory Drug

Boxed warning

None
None

Half-life

about 20 minutes (the label also states 0.33 hours) for aspirin itself
about 1.8 to 2.0 hours

Treats

Rheumatoid Arthritis, Fever, Gout
Juvenile Arthritis, Rheumatoid Arthritis, Bursitis

Get junior strength advilhigher-rated option

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Where to buy

Buy over-the-counter from trusted retailers.

Frequently asked questions

What is the difference between 8-Hour Bayer and Junior Strength Advil?

8-Hour Bayer contains Aspirin, while Junior Strength Advil contains Ibuprofen — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.