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8-HOUR BAYER vs ADVIL

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Rating

New
72/100

Pharmacy pays

~$0.78 /30
$0.04 /mL

Type

RX
OTC

Active ingredient

ASPIRIN
IBUPROFEN

Dosage forms

Tablet, extended release
Tablet, Capsule

Drug class

Nonsteroidal Anti-Inflammatory Drug
Nonsteroidal Anti-Inflammatory Drug

Boxed warning

None
None

Half-life

about 20 minutes (the label also states 0.33 hours) for aspirin itself
about 1.8 to 2.0 hours

Treats

Rheumatoid Arthritis, Fever, Gout
Juvenile Arthritis, Rheumatoid Arthritis, Bursitis

Get advilhigher-rated option

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Where to buy

Buy over-the-counter from trusted retailers.

Frequently asked questions

What is the difference between 8-Hour Bayer and Advil?

8-Hour Bayer contains Aspirin, while Advil contains Ibuprofen — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.