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P2Y12 Platelet Inhibitor drugs compared

Compare all 5 P2Y12 Platelet Inhibitor drugs side by side. They share one FDA-defined mechanism but differ in approved uses, prescription status, brand-vs-generic options, price, and FDA recall-safety record — which our independent rating scores. The highest-rated is effient.

Top-rated p2y12 platelet inhibitor: 1. Effient · 2. Kengreal · 3. Plavix

P2Y12 Platelet Inhibitor drugs compared side by side, with pharmaranks' FDA recall-safety rating
DrugGenericSafety ratingFDA recall-based
EffientPrasugrel Hydrochloride70/100
KengrealCangrelor70/100
PlavixClopidogrel Bisulfate70/100
Clopidogrel Bisulfate66/100
CangrelorNot yet rated

The safety rating column is unique to pharmaranks — an independent 0–100 score from FDA regulatory recall data. Higher is safer. Not medical advice.

Full ranking · 5 drugs

  1. 1

    effient

    Prasugrel Hydrochloride

    70/100
  2. 2

    kengreal

    Cangrelor

    70/100
  3. 3

    plavix

    Clopidogrel Bisulfate

    70/100
  4. 4

    clopidogrel bisulfate

    Clopidogrel Bisulfate

    66/100
  5. 5

    cangrelor

    Cangrelor

    New

Frequently asked questions

What is the P2Y12 Platelet Inhibitor drug class?

P2Y12 Platelet Inhibitor is an FDA Established Pharmacologic Class (EPC) — a group of drugs that share a mechanism of action. pharmaranks lists 5 P2Y12 Platelet Inhibitor products, each independently rated.

Are all P2Y12 Platelet Inhibitor drugs the same?

No. P2Y12 Platelet Inhibitor drugs share the same core mechanism — that is why they sit in one FDA class — but they differ in their approved uses, available forms, whether they are prescription or over-the-counter, brand-vs-generic options and price, and their FDA recall-safety record.

Which P2Y12 Platelet Inhibitor drug is best-rated?

By our independent rating, effient currently ranks highest among P2Y12 Platelet Inhibitor drugs. Ratings are based on FDA regulatory (recall-safety) data — always consult a professional.

Sources: the P2Y12 Platelet Inhibitor class definition and its member drugs come from the U.S. NLM RxClass (Established Pharmacologic Class). Ratings are pharmaranks’ independent FDA recall-safety analysis.