Muscle Relaxant drugs compared

Compare all 8 Muscle Relaxant drugs side by side, used for conditions such as muscle cramp, muscle rigidity, myositis. They share one FDA-defined mechanism but differ in approved uses, prescription status, brand-vs-generic options, price, and FDA recall-safety record — which our independent rating scores. The highest-rated is robaxin.

Top-rated muscle relaxant: 1. Robaxin · 2. Metaxalone · 3. Amrix

Muscle Relaxant drugs compared side by side, with pharmaranks' FDA recall-safety rating
Drug	Generic	Form	Status	Used for	Safety ratingFDA recall-based	Pharmacy pays
Robaxin	Methocarbamol	Injectable	Prescription	Muscle Cramp, Muscle Rigidity	72/100	$1
Metaxalone	—	Tablet	Prescription	Muscle Cramp, Muscle Rigidity	70/100	$12
Amrix	Cyclobenzaprine Hydrochloride	Capsule	Prescription	Muscle Cramp, Muscle Rigidity	56/100	$1
Atmeksi	Methocarbamol	Suspension	Prescription	Muscle Cramp, Muscle Rigidity	Not yet rated	$1
Carisoprodol	—	Tablet	Prescription	Muscle Cramp, Muscle Rigidity	Not yet rated	$2
Methocarbamol	—	Injectable	Prescription	Muscle Cramp, Muscle Rigidity	Not yet rated	$1
Soma	Carisoprodol	Tablet	Prescription	Muscle Cramp, Muscle Rigidity	Not yet rated	$2
Tonmya	Cyclobenzaprine Hydrochloride	Tablet	Prescription	Muscle Cramp, Muscle Rigidity	Not yet rated	$1

The safety rating column is unique to pharmaranks — an independent 0–100 score from FDA regulatory recall data. Higher is safer. Not medical advice.

Best muscle relaxant by condition

for muscle cramp for muscle rigidity for myositis for pain for spasm for tetanus

Full ranking · 8 drugs

Frequently asked questions

What is the Muscle Relaxant drug class?

Muscle Relaxant is an FDA Established Pharmacologic Class (EPC) — a group of drugs that share a mechanism of action. pharmaranks lists 8 Muscle Relaxant products, each independently rated.

Are all Muscle Relaxant drugs the same?

No. Muscle Relaxant drugs share the same core mechanism — that is why they sit in one FDA class — but they differ in their approved uses, available forms, whether they are prescription or over-the-counter, brand-vs-generic options and price, and their FDA recall-safety record.

What conditions do Muscle Relaxant drugs treat?

Per NIH RxClass drug-classification data, Muscle Relaxant drugs are used for conditions including muscle cramp, muscle rigidity, myositis, pain, spasm, tetanus.

Which Muscle Relaxant drug is best-rated?

By our independent rating, robaxin currently ranks highest among Muscle Relaxant drugs. Ratings are based on FDA regulatory (recall-safety) data — always consult a professional.

Sources: the Muscle Relaxant class definition and its member drugs come from the U.S. NLM RxClass (Established Pharmacologic Class); how the class works is summarized from Cyclobenzaprine - StatPearls - NCBI Bookshelf. Ratings are pharmaranks’ independent FDA recall-safety analysis.