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Calcium channel blockers compared

Compare all 10 calcium channel blockers side by side, used for conditions such as angina pectoris, variant, coronary artery disease, hypertension. Calcium channel blockers are the Calcium Channel Blocker class. They share one FDA-defined mechanism but differ in approved uses, prescription status, brand-vs-generic options, price, and FDA recall-safety record — which our independent rating scores. The highest-rated is amlodipine besylate.

Top-rated calcium channel blocker: 1. Amlodipine Besylate · 2. Norvasc · 3. Verapamil Hydrochloride

Calcium Channel Blocker drugs compared side by side, with pharmaranks' FDA recall-safety rating
DrugGenericSafety ratingFDA recall-based
Amlodipine Besylate72/100
NorvascAmlodipine Besylate70/100
Verapamil Hydrochloride70/100
VerelanVerapamil Hydrochloride70/100
Verelan PmVerapamil Hydrochloride70/100
Cardizem CdDiltiazem HydrochlorideNot yet rated
Cardizem LaDiltiazem HydrochlorideNot yet rated
NorliqvaAmlodipine BesylateNot yet rated
SdamloAmlodipine BesylateNot yet rated
TiazacDiltiazem HydrochlorideNot yet rated

The safety rating column is unique to pharmaranks — an independent 0–100 score from FDA regulatory recall data. Higher is safer. Not medical advice.

Full ranking · 10 drugs

  1. 1

    amlodipine besylate

    Amlodipine Besylate

    72/100
  2. 2

    norvasc

    Amlodipine Besylate

    70/100
  3. 3

    verapamil hydrochloride

    Verapamil Hydrochloride

    70/100
  4. 4

    verelan

    Verapamil Hydrochloride

    70/100
  5. 5

    verelan pm

    Verapamil Hydrochloride

    70/100
  6. 6

    cardizem cd

    Diltiazem Hydrochloride

    New
  7. 7

    cardizem la

    Diltiazem Hydrochloride

    New
  8. 8

    norliqva

    Amlodipine Besylate

    New
  9. 9

    sdamlo

    Amlodipine Besylate

    New
  10. 10

    tiazac

    Diltiazem Hydrochloride

    New

Frequently asked questions

What is the Calcium Channel Blocker drug class?

Calcium Channel Blocker is an FDA Established Pharmacologic Class (EPC) — a group of drugs that share a mechanism of action. pharmaranks lists 10 Calcium Channel Blocker products, each independently rated.

Are all Calcium Channel Blocker drugs the same?

No. Calcium Channel Blocker drugs share the same core mechanism — that is why they sit in one FDA class — but they differ in their approved uses, available forms, whether they are prescription or over-the-counter, brand-vs-generic options and price, and their FDA recall-safety record.

Is "calcium channel blockers" the same as the Calcium Channel Blocker class?

Yes — "calcium channel blockers" is the everyday name for the Calcium Channel Blocker drug class. This page compares the 10 calcium channel blockers pharmaranks rates, with our independent FDA recall-safety score for each.

What conditions do Calcium Channel Blocker drugs treat?

Per NIH RxClass drug-classification data, Calcium Channel Blocker drugs are used for conditions including angina pectoris, variant, coronary artery disease, hypertension, atrial fibrillation, atrial flutter, myocardial infarction.

Which Calcium Channel Blocker drug is best-rated?

By our independent rating, amlodipine besylate currently ranks highest among Calcium Channel Blocker drugs. Ratings are based on FDA regulatory (recall-safety) data — always consult a professional.

Sources: the Calcium Channel Blocker class definition and its member drugs come from the U.S. NLM RxClass (Established Pharmacologic Class); how the class works is summarized from Calcium Channel Blockers - StatPearls - NCBI Bookshelf. Ratings are pharmaranks’ independent FDA recall-safety analysis.