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Aromatase Inhibitor drugs compared

Compare all 4 Aromatase Inhibitor drugs side by side, used for conditions such as breast neoplasms. They share one FDA-defined mechanism but differ in approved uses, prescription status, brand-vs-generic options, price, and FDA recall-safety record — which our independent rating scores. The highest-rated is exemestane.

Top-rated aromatase inhibitor: 1. Exemestane · 2. Arimidex · 3. Femara

Aromatase Inhibitor drugs compared side by side, with pharmaranks' FDA recall-safety rating
DrugGenericSafety ratingFDA recall-based
Exemestane—72/100
ArimidexAnastrozole70/100
FemaraLetrozole70/100
AromasinExemestane64/100

The safety rating column is unique to pharmaranks — an independent 0–100 score from FDA regulatory recall data. Higher is safer. Not medical advice.

Best aromatase inhibitor by condition

for breast neoplasms

Full ranking · 4 drugs

  1. 1

    exemestane

    Exemestane

    72/100
  2. 2

    arimidex

    Anastrozole

    70/100
  3. 3

    femara

    Letrozole

    70/100
  4. 4

    aromasin

    Exemestane

    64/100

Frequently asked questions

What is the Aromatase Inhibitor drug class?

Aromatase Inhibitor is an FDA Established Pharmacologic Class (EPC) — a group of drugs that share a mechanism of action. pharmaranks lists 4 Aromatase Inhibitor products, each independently rated.

Are all Aromatase Inhibitor drugs the same?

No. Aromatase Inhibitor drugs share the same core mechanism — that is why they sit in one FDA class — but they differ in their approved uses, available forms, whether they are prescription or over-the-counter, brand-vs-generic options and price, and their FDA recall-safety record.

What conditions do Aromatase Inhibitor drugs treat?

Per NIH RxClass drug-classification data, Aromatase Inhibitor drugs are used for conditions including breast neoplasms.

Which Aromatase Inhibitor drug is best-rated?

By our independent rating, exemestane currently ranks highest among Aromatase Inhibitor drugs. Ratings are based on FDA regulatory (recall-safety) data — always consult a professional.

Sources: the Aromatase Inhibitor class definition and its member drugs come from the U.S. NLM RxClass (Established Pharmacologic Class). Ratings are pharmaranks’ independent FDA recall-safety analysis.