Antirheumatic Agent drugs compared

Compare all 4 Antirheumatic Agent drugs side by side, used for conditions such as arthritis, rheumatoid, cystinuria, hepatolenticular degeneration. They share one FDA-defined mechanism but differ in approved uses, prescription status, brand-vs-generic options, price, and FDA recall-safety record — which our independent rating scores. The highest-rated is cuprimine.

3 of 4 drugs in this class carry a pharmaranks safety score, ranging 70–74 out of 100 — computed from FDA recall records, not from reviews.

Rated against independent sources·Last updated July 30, 2026·How we rate

Top-rated antirheumatic agent: 1. Cuprimine · 2. Penicillamine · 3. Arava

Antirheumatic Agent drugs compared side by side, with pharmaranks' FDA recall-safety rating
Drug	Generic	Form	Status	Used for	Safety ratingFDA recall-based	Pharmacy pays
Cuprimine	Penicillamine	Capsule	Prescription	Arthritis, Rheumatoid, Cystinuria	74/100	—
Penicillamine	—	Capsule	Prescription	Arthritis, Rheumatoid, Cystinuria	72/100	—
Arava	Leflunomide	Tablet	Prescription	Arthritis, Rheumatoid	70/100	$9
Depen	Penicillamine	Tablet	Prescription	Arthritis, Rheumatoid, Cystinuria	Not yet rated	—

The safety rating column is unique to pharmaranks — an independent 0–100 score from FDA regulatory recall data. Higher is safer. Not medical advice.

Best antirheumatic agent by condition

for rheumatoid arthritis for cystinuria for hepatolenticular degeneration for lead poisoning for biliary liver cirrhosis for mercury poisoning

Full ranking · 4 drugs

Frequently asked questions

What is the Antirheumatic Agent drug class?

Antirheumatic Agent is an FDA Established Pharmacologic Class (EPC) — a group of drugs that share a mechanism of action. pharmaranks lists 4 Antirheumatic Agent products, each independently rated.

Are all Antirheumatic Agent drugs the same?

No. Antirheumatic Agent drugs share the same core mechanism — that is why they sit in one FDA class — but they differ in their approved uses, available forms, whether they are prescription or over-the-counter, brand-vs-generic options and price, and their FDA recall-safety record.

What conditions do Antirheumatic Agent drugs treat?

Per NIH RxClass drug-classification data, Antirheumatic Agent drugs are used for conditions including arthritis, rheumatoid, cystinuria, hepatolenticular degeneration, lead poisoning, liver cirrhosis, biliary, mercury poisoning.

Which Antirheumatic Agent drug is best-rated?

By our independent rating, cuprimine currently ranks highest among Antirheumatic Agent drugs. Ratings are based on FDA regulatory (recall-safety) data — always consult a professional.

Sources: the Antirheumatic Agent class definition and its member drugs come from the U.S. NLM RxClass (Established Pharmacologic Class). Ratings are pharmaranks’ independent FDA recall-safety analysis.