Can you take solriamfetol while breastfeeding?
What LactMed says
The National Library of Medicine’s own summary, quoted in full. We do not write a verdict of our own on this question, and we do not compress theirs into a label.
No information is available on the clinical use of solriamfetol during breastfeeding. However, amounts in breastmilk appear to be low and would not be expected to cause any adverse effects in breastfed infants. If solriamfetol is required by the mother, it is not a reason to discontinue breastfeeding. Monitor the breastfed infant for adverse reactions, such agitation, insomnia, and reduced weight gain.
Quoted from Solriamfetol — Drugs and Lactation Database (LactMed®), National Institute of Child Health and Human Development, revised April 15, 2025.
What LactMed would consider instead
LactMed ends this record by naming the drugs it would consider in place of solriamfetol. Whether any of them fits depends on what you are treating — this is the database’s list, not a recommendation from us.
- Amphetamine
- Armodafinil
- Dextroamphetamine
- Lisdexamfetamine
- Methylphenidate
- Modafinil
- Oxybate Salts
- Pitolisant
How much solriamfetol gets into breastmilk
Maternal Levels. The manufacturer reports that a single-dose milk and plasma lactation study was conducted in 6 healthy adult lactating women who were between 10 days and 52 weeks postpartum. They were given a single oral 150 mg dose of solriamfetol. The daily infant dose is 0.112 mg/kg based on infant weight of 6 kg. The cumulative median amount excreted in breastmilk was 0.67 mg over 72 hours, which is about 5.5% of the weight-adjusted maternal dose. Of the total amount of solriamfetol excreted in breastmilk over 72 hours, approximately 78% and 98% were excreted by 8 and 24 hours, respectively, with an apparent mean elimination half-life in breast milk of about 5 hours.
Infant Levels. Relevant published information was not found as of the revision date.
What has been seen in breastfed infants
Relevant published information was not found as of the revision date.
Effects on milk supply
Relevant published information was not found as of the revision date.
Frequently asked questions
Can you take solriamfetol while breastfeeding?
No information is available on the clinical use of solriamfetol during breastfeeding. The full record is quoted on this page, and the decision is one to make with the person who prescribed it — LactMed itself states it is not a substitute for professional judgement.
What can I take instead of solriamfetol while breastfeeding?
LactMed lists Amphetamine, Armodafinil, Dextroamphetamine, Lisdexamfetamine, Methylphenidate, Modafinil, Oxybate Salts, Pitolisant as alternate drugs to consider. That is the database's own list for this drug — whether any of them suits you depends on what you are treating.
Does solriamfetol pass into breastmilk?
LactMed's measured drug levels for solriamfetol are quoted in full on this page, under "How much gets into breastmilk".
Do I need to pump and dump after taking solriamfetol?
LactMed does not frame its records that way — it reports measured drug levels in milk and what has been observed in breastfed infants, which is what this page quotes. "Pump and dump" advice for a specific drug and dose should come from your clinician or a pharmacist, not from a general rule.
More on solriamfetol
LactMed states that the information it presents is not a substitute for professional judgement, and that you should consult your healthcare provider for breastfeeding advice related to your particular situation. Nothing on this page is medical advice.