Can you take rifabutin while breastfeeding?
What LactMed says
The National Library of Medicine’s own summary, quoted in full. We do not write a verdict of our own on this question, and we do not compress theirs into a label.
The amount of rifabutin in milk is insufficient to treat tuberculosis in the breastfed infant. The Centers for Disease Control and Prevention and other professional organizations state that breastfeeding should not be discouraged in women taking rifabutin. Monitor the infant for signs of liver toxicity. Breastmilk may be stained a brown-orange color.
Quoted from Rifabutin — Drugs and Lactation Database (LactMed®), National Institute of Child Health and Human Development, revised May 15, 2022.
What LactMed would consider instead
LactMed ends this record by naming the drugs it would consider in place of rifabutin. Whether any of them fits depends on what you are treating — this is the database’s list, not a recommendation from us.
- Rifampin
- Rifapentin
How much rifabutin gets into breastmilk
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
What has been seen in breastfed infants
Relevant published information was not found as of the revision date.
Effects on milk supply
Relevant published information was not found as of the revision date.
Frequently asked questions
Can you take rifabutin while breastfeeding?
The amount of rifabutin in milk is insufficient to treat tuberculosis in the breastfed infant. The full record is quoted on this page, and the decision is one to make with the person who prescribed it — LactMed itself states it is not a substitute for professional judgement.
What can I take instead of rifabutin while breastfeeding?
LactMed lists Rifampin, Rifapentin as alternate drugs to consider. That is the database's own list for this drug — whether any of them suits you depends on what you are treating.
Does rifabutin pass into breastmilk?
LactMed's measured drug levels for rifabutin are quoted in full on this page, under "How much gets into breastmilk".
Do I need to pump and dump after taking rifabutin?
LactMed does not frame its records that way — it reports measured drug levels in milk and what has been observed in breastfed infants, which is what this page quotes. "Pump and dump" advice for a specific drug and dose should come from your clinician or a pharmacist, not from a general rule.
More on rifabutin
LactMed states that the information it presents is not a substitute for professional judgement, and that you should consult your healthcare provider for breastfeeding advice related to your particular situation. Nothing on this page is medical advice.