Can you take pasireotide while breastfeeding?
What LactMed says
The National Library of Medicine’s own summary, quoted in full. We do not write a verdict of our own on this question, and we do not compress theirs into a label.
The excretion of pasireotide into breastmilk has not been studied. However, because it has a high molecular weight of 1047 daltons it is likely to be poorly excreted into breastmilk and it is a peptide that is likely digested in the infant's gastrointestinal tract. It is unlikely to reach the clinically important levels in infant serum. However, the manufacturer states that nursing mothers should not use pasireotide. An alternate drug is preferred.
Quoted from Pasireotide — Drugs and Lactation Database (LactMed®), National Institute of Child Health and Human Development, revised November 30, 2022.
What LactMed would consider instead
LactMed ends this record by naming the drugs it would consider in place of pasireotide. Whether any of them fits depends on what you are treating — this is the database’s list, not a recommendation from us.
How much pasireotide gets into breastmilk
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
What has been seen in breastfed infants
Relevant published information was not found as of the revision date.
Effects on milk supply
Relevant published information was not found as of the revision date.
Frequently asked questions
Can you take pasireotide while breastfeeding?
The excretion of pasireotide into breastmilk has not been studied. The full record is quoted on this page, and the decision is one to make with the person who prescribed it — LactMed itself states it is not a substitute for professional judgement.
What can I take instead of pasireotide while breastfeeding?
LactMed lists Octreotide as alternate drugs to consider. That is the database's own list for this drug — whether any of them suits you depends on what you are treating.
Does pasireotide pass into breastmilk?
LactMed's measured drug levels for pasireotide are quoted in full on this page, under "How much gets into breastmilk".
Do I need to pump and dump after taking pasireotide?
LactMed does not frame its records that way — it reports measured drug levels in milk and what has been observed in breastfed infants, which is what this page quotes. "Pump and dump" advice for a specific drug and dose should come from your clinician or a pharmacist, not from a general rule.
More on pasireotide
LactMed states that the information it presents is not a substitute for professional judgement, and that you should consult your healthcare provider for breastfeeding advice related to your particular situation. Nothing on this page is medical advice.