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Can you take caspofungin while breastfeeding?

By the pharmaranks editorial teamReviewed against the NIH/NLM Drugs and Lactation Database (LactMed) sourcesUpdated May 15, 2023How we research

What LactMed says

The National Library of Medicine’s own summary, quoted in full. We do not write a verdict of our own on this question, and we do not compress theirs into a label.

No information is available on the use of caspofungin during breastfeeding. Because caspofungin is 97% bound to plasma proteins and has poor oral bioavailability, it is unlikely to reach the milk and be absorbed by the infant. Caspofungin can safely be given intravenously to infants of aged 3 months or older. Any amount absorbed from milk is likely to be far less than an infant dose. If caspofungin is required by the mother, it is not a reason to discontinue breastfeeding.

Quoted from Caspofungin — Drugs and Lactation Database (LactMed®), National Institute of Child Health and Human Development, revised May 15, 2023.

What LactMed would consider instead

LactMed ends this record by naming the drugs it would consider in place of caspofungin. Whether any of them fits depends on what you are treating — this is the database’s list, not a recommendation from us.

How much caspofungin gets into breastmilk

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

What has been seen in breastfed infants

Relevant published information was not found as of the revision date.

Effects on milk supply

Relevant published information was not found as of the revision date.

Frequently asked questions

Can you take caspofungin while breastfeeding?

No information is available on the use of caspofungin during breastfeeding. The full record is quoted on this page, and the decision is one to make with the person who prescribed it — LactMed itself states it is not a substitute for professional judgement.

What can I take instead of caspofungin while breastfeeding?

LactMed lists Fluconazole, Miconazole as alternate drugs to consider. That is the database's own list for this drug — whether any of them suits you depends on what you are treating.

Does caspofungin pass into breastmilk?

LactMed's measured drug levels for caspofungin are quoted in full on this page, under "How much gets into breastmilk".

Do I need to pump and dump after taking caspofungin?

LactMed does not frame its records that way — it reports measured drug levels in milk and what has been observed in breastfed infants, which is what this page quotes. "Pump and dump" advice for a specific drug and dose should come from your clinician or a pharmacist, not from a general rule.

More on caspofungin

LactMed states that the information it presents is not a substitute for professional judgement, and that you should consult your healthcare provider for breastfeeding advice related to your particular situation. Nothing on this page is medical advice.