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Can you take argatroban while breastfeeding?

By the pharmaranks editorial teamReviewed against the NIH/NLM Drugs and Lactation Database (LactMed) sourcesUpdated Jul 15, 2023How we research

What LactMed says

The National Library of Medicine’s own summary, quoted in full. We do not write a verdict of our own on this question, and we do not compress theirs into a label.

Because argatroban is poorly absorbed orally, it might not adversely affect a breastfeeding infant. However, no information is available on the use of argatroban during breastfeeding, so an alternate drug is preferred.

Quoted from Argatroban — Drugs and Lactation Database (LactMed®), National Institute of Child Health and Human Development, revised July 15, 2023.

How much argatroban gets into breastmilk

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

What has been seen in breastfed infants

Relevant published information was not found as of the revision date.

Effects on milk supply

Relevant published information was not found as of the revision date.

Frequently asked questions

Can you take argatroban while breastfeeding?

Because argatroban is poorly absorbed orally, it might not adversely affect a breastfeeding infant. The full record is quoted on this page, and the decision is one to make with the person who prescribed it — LactMed itself states it is not a substitute for professional judgement.

Does argatroban pass into breastmilk?

LactMed's measured drug levels for argatroban are quoted in full on this page, under "How much gets into breastmilk".

Do I need to pump and dump after taking argatroban?

LactMed does not frame its records that way — it reports measured drug levels in milk and what has been observed in breastfed infants, which is what this page quotes. "Pump and dump" advice for a specific drug and dose should come from your clinician or a pharmacist, not from a general rule.

More on argatroban

LactMed states that the information it presents is not a substitute for professional judgement, and that you should consult your healthcare provider for breastfeeding advice related to your particular situation. Nothing on this page is medical advice.