Best Tricyclic Antidepressant for pain
3 Tricyclic Antidepressant drugs indicated for pain, ranked by our independent rating. The current highest-rated is imipramine hydrochloride. Compare them with all treatments for pain or the full Tricyclic Antidepressant class. Not medical advice — always consult a professional.
Top tricyclic antidepressant for pain: 1. Imipramine Hydrochloride · 2. Anafranil · 3. Zonalon
| # | Drug | Rating | Type | Typical price | |
|---|---|---|---|---|---|
| 1 | Imipramine Hydrochloride | 70/100 | Prescription | $3 | View → |
| 2 | Anafranil | 70/100 | Prescription | $7 | View → |
| 3 | Zonalon |
Full ranking · 3 drugs
Frequently asked
- What is the best tricyclic antidepressant for pain?
- By our independent rating, imipramine hydrochloride currently ranks highest among Tricyclic Antidepressant drugs used for pain. Ratings are based on FDA regulatory (recall-safety) data — always consult a professional.
- Which tricyclic antidepressant drugs treat pain?
- pharmaranks lists 3 Tricyclic Antidepressant products indicated for pain, per FDA drug-label data — each independently rated and ranked above.
- How are these ranked?
- By our independent score, currently based on FDA regulatory recall-safety data (the methodology blends additional sources as they come online). See the How we rate page.