Which parenteral iron replacement drugs treat anemia, iron-deficiency?

pharmaranks lists 4 Parenteral Iron Replacement products used for anemia, iron-deficiency, per NIH RxClass drug-classification data — each independently rated and ranked above.

How are these ranked?

By our independent score, currently based on FDA regulatory recall-safety data (the methodology blends additional sources as they come online). See the How we rate page.

Best Parenteral Iron Replacement for anemia, iron-deficiency

Top-rated pick: Ferabright — pharmaranks score 70/100, the highest of the 4 Parenteral Iron Replacement drugs used for anemia, iron-deficiency, ranked by our independent FDA recall-safety score. Compare them with all treatments for anemia, iron-deficiency or the full Parenteral Iron Replacement class. Not medical advice — always consult a professional.

Quick answer: Of the 4 parenteral iron replacement drugs we rate for anemia, iron-deficiency, none are yet flagged as generics in our price data, and most are injectable. Our ranking reflects each drug’s FDA recall-safety record — not clinical effectiveness for anemia, iron-deficiency; the right choice depends on your situation, so confirm it with your prescriber.

Rated against independent regulatory sources·Last updated August 19, 2026·How we rate

How parenteral iron replacement work

Given by injection or IV, these supply iron directly into the bloodstream wrapped in a protective carbohydrate shell. The iron is gradually released, picked up by the protein transferrin, and delivered to the bone marrow, where it is used to build hemoglobin and treat iron-deficiency anemia.

Source: Iron Dextran - StatPearls - NCBI Bookshelf

Top parenteral iron replacement for anemia, iron-deficiency: 1. Ferabright · 2. Feraheme · 3. Ferrlecit

Best-rated Parenteral Iron Replacement for anemia, iron-deficiency, ranked by pharmaranks score
#	Drug	Rating	Type	Form	Generic?	Pharmacy pays
1	Ferabright Boxed warning	70/100	Prescription	Injectable	No data	—	View →
2	Feraheme Boxed warning	70/100	Prescription	Injectable	No data	—	View →
3	Ferrlecit	70/100	Prescription	Injectable	No data	—	View →
4	Venofer	Not yet rated	Prescription	Injectable	No data	—	View →

Full ranking · 4 drugs

#2 of 4 in Parenteral Iron Replacement

ferabright

Boxed warning

PrescriptionFDA-sourced

70/100

Ferabright (Ferumoxytol) is a parenteral iron replacement used to treat Iron-Deficiency Anemia.

(3 data points)

parenteral iron replacementanemia, iron-deficiency

Price varies

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#2 of 4 in Parenteral Iron Replacement

feraheme

Boxed warning

PrescriptionFDA-sourced

70/100

Feraheme (Ferumoxytol) is a parenteral iron replacement used to treat Iron-Deficiency Anemia.

(3 data points)

parenteral iron replacementanemia, iron-deficiency

Price varies

View details →

#2 of 4 in Parenteral Iron Replacement

ferrlecit

PrescriptionFDA-sourced

70/100

Ferrlecit (Sodium Ferric Gluconate Complex) is a parenteral iron replacement used to treat Hematologic Pregnancy Complications, Iron-Deficiency Anemia.

(1 data points)

parenteral iron replacementphosphate binderpregnancy complications, hematologic

Price varies

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venofer

PrescriptionFDA-sourced

New

Venofer (Iron Sucrose) is a parenteral iron replacement used to treat Hematologic Pregnancy Complications, Iron-Deficiency Anemia.

parenteral iron replacementphosphate binderpregnancy complications, hematologic

Price varies

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Frequently asked

What is the best parenteral iron replacement for anemia, iron-deficiency?: By our independent recall-safety rating — not an efficacy measure — ferabright ranks highest among Parenteral Iron Replacement drugs used for anemia, iron-deficiency. Always consult a professional.
Which parenteral iron replacement drugs treat anemia, iron-deficiency?: pharmaranks lists 4 Parenteral Iron Replacement products used for anemia, iron-deficiency, per NIH RxClass drug-classification data — each independently rated and ranked above.
How are these ranked?: By our independent score, currently based on FDA regulatory recall-safety data (the methodology blends additional sources as they come online). See the How we rate page.