Best HMG-CoA Reductase Inhibitor for coronary artery disease
Top-rated pick: Crestor — pharmaranks score 70/100, the highest of the 7 HMG-CoA Reductase Inhibitor drugs used for coronary artery disease, ranked by our independent FDA recall-safety score. Compare them with all treatments for coronary artery disease or the full HMG-CoA Reductase Inhibitor class. Not medical advice — always consult a professional.
Quick answer: Of the 7 HMG-CoA reductase inhibitor drugs we rate for coronary artery disease, all are available as lower-cost generics, and most are tablet. Our ranking reflects each drug’s FDA recall-safety record — not clinical effectiveness for coronary artery disease; the right choice depends on your situation, so confirm it with your prescriber.
How HMG-CoA reductase inhibitor work
Statins block HMG-CoA reductase, the key enzyme the liver uses to make cholesterol. With less cholesterol being produced, the liver pulls more LDL ("bad") cholesterol out of the blood, lowering overall blood cholesterol levels.
Source: HMG-CoA Reductase Inhibitors - StatPearls - NCBI Bookshelf
Other drug classes for coronary artery disease
Top hmg-coa reductase inhibitor for coronary artery disease: 1. Crestor · 2. Zocor · 3. Lescol XL
| # | Drug | Rating | Type | Form | Generic? | Pharmacy pays | |
|---|---|---|---|---|---|---|---|
| 1 | 70/100 | Prescription | Tablet | Generic | $1 | View → | |
| 2 | 70/100 | Prescription | Tablet | Generic | $1 | View → | |
| 3 | 68/100 | Prescription | Tablet | Generic | $86 | View → | |
| 4 | 62/100 | Prescription | Tablet | Generic | $1 | View → | |
| 5 | Not yet rated | Prescription | Suspension | Generic | $1 | View → | |
| 6 | Not yet rated | Prescription | Suspension | Generic | $1 | View → | |
| 7 | Not yet rated | Prescription | Tablet | Generic | $1 | View → |
Full ranking · 7 drugs
crestor
PrescriptionFDA-sourced
Crestor (Rosuvastatin Calcium) is a HMG-CoA reductase inhibitor used to treat Coronary Artery Disease, Hypercholesterolemia, Hyperlipoproteinemias, Hypertriglyceridemia.
Pharmacy pays
From ~$1.04/30· 4 forms Save up to 32% in class
zocor
PrescriptionFDA-sourced
Zocor (Simvastatin) is a HMG-CoA reductase inhibitor used to treat Coronary Artery Disease, Hypercholesterolemia, Hyperlipoproteinemias, Hypertriglyceridemia.
Pharmacy pays
From ~$0.84/30· 5 forms
lescol xl
PrescriptionFDA-sourced
Lescol XL (Fluvastatin Sodium) is a HMG-CoA reductase inhibitor used to treat Coronary Artery Disease, Hypercholesterolemia, Hyperlipoproteinemias, Hypertriglyceridemia.
Pharmacy pays
From ~$75.75/30· 3 forms Save up to 99% in classlovastatin
PrescriptionFDA-sourced
Lovastatin is a HMG-CoA reductase inhibitor used to treat Coronary Artery Disease, Hypercholesterolemia, Hyperlipoproteinemias, Hypertriglyceridemia.
Pharmacy pays
From ~$1.14/30· 3 forms Save up to 29% in classatorvaliq
PrescriptionFDA-sourced
Atorvaliq (Atorvastatin Calcium) is a HMG-CoA reductase inhibitor used to treat Coronary Artery Disease, Hypercholesterolemia, Hyperlipoproteinemias, Hypertriglyceridemia.
Pharmacy pays
From ~$0.75/30· 4 formsflolipid
PrescriptionFDA-sourced
Flolipid (Simvastatin) is a HMG-CoA reductase inhibitor used to treat Coronary Artery Disease, Hypercholesterolemia, Hyperlipoproteinemias, Hypertriglyceridemia.
Pharmacy pays
From ~$0.84/30· 5 forms
lipitor
PrescriptionFDA-sourced
Lipitor (Atorvastatin Calcium) is a HMG-CoA reductase inhibitor used to treat Coronary Artery Disease, Hypercholesterolemia, Hyperlipoproteinemias, Hypertriglyceridemia.
Pharmacy pays
From ~$0.75/30· 4 formsFrequently asked
- What is the best hmg-coa reductase inhibitor for coronary artery disease?
- By our independent recall-safety rating — not an efficacy measure — crestor ranks highest among HMG-CoA Reductase Inhibitor drugs used for coronary artery disease. Always consult a professional.
- Which hmg-coa reductase inhibitor drugs treat coronary artery disease?
- pharmaranks lists 7 HMG-CoA Reductase Inhibitor products used for coronary artery disease, per NIH RxClass drug-classification data — each independently rated and ranked above.
- How are these ranked?
- By our independent score, currently based on FDA regulatory recall-safety data (the methodology blends additional sources as they come online). See the How we rate page.