How are these ranked?

By our independent score, currently based on FDA regulatory recall-safety data (the methodology blends additional sources as they come online). See the How we rate page.

Best Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor for hepatitis b, chronic

Top-rated pick: Baraclude — pharmaranks score 72/100, the highest of the 2 Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor drugs used for hepatitis b, chronic, ranked by our independent FDA recall-safety score. Compare them with all treatments for hepatitis b, chronic or the full Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor class. Not medical advice — always consult a professional.

Quick answer: Of the 2 hepatitis b virus nucleoside analog reverse transcriptase inhibitor drugs we rate for hepatitis b, chronic, all are available as lower-cost generics, and most are solution. Our ranking reflects each drug’s FDA recall-safety record — not clinical effectiveness for hepatitis b, chronic; the right choice depends on your situation, so confirm it with your prescriber.

Rated against independent regulatory sources·Last updated August 19, 2026·How we rate

Top hepatitis b virus nucleoside analog reverse transcriptase inhibitor for hepatitis b, chronic: 1. Baraclude · 2. Viread

Best-rated Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor for hepatitis b, chronic, ranked by pharmaranks score
#	Drug	Rating	Type	Form	Generic?	Pharmacy pays
1	Baraclude Boxed warning	72/100	Prescription	Solution	Generic	$7	View →
2	Viread Boxed warning	70/100	Prescription	Powder	Generic	$10	View →

Full ranking · 2 drugs

#1 of 4 in Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor

baraclude

Boxed warning

PrescriptionFDA-sourced

72/100

Baraclude (Entecavir) is a hepatitis b virus nucleoside analog reverse transcriptase inhibitor used to treat Chronic Hepatitis B.

(4 data points)

hepatitis b virus nucleoside analog reverse transcriptase inhibitorhepatitis b, chronic

Pharmacy pays

From ~$6.39/30· 2 forms

View details →

#2 of 4 in Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor

viread

Boxed warning

PrescriptionFDA-sourced

70/100

Viread (Tenofovir Disoproxil Fumarate) is a hepatitis b virus nucleoside analog reverse transcriptase inhibitor used to treat Chronic Hepatitis B, Acquired Immunodeficiency Syndrome.

(4 data points)

hepatitis b virus nucleoside analog reverse transcriptase inhibitorhuman immunodeficiency virus nucleoside analog reverse transcriptase inhibitorhepatitis b, chronic

Pharmacy pays

~$9.50 /30

Save up to 28% in class

View details →

Frequently asked

What is the best hepatitis b virus nucleoside analog reverse transcriptase inhibitor for hepatitis b, chronic?: By our independent recall-safety rating — not an efficacy measure — baraclude ranks highest among Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor drugs used for hepatitis b, chronic. Always consult a professional.
Which hepatitis b virus nucleoside analog reverse transcriptase inhibitor drugs treat hepatitis b, chronic?: pharmaranks lists 2 Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor products used for hepatitis b, chronic, per NIH RxClass drug-classification data — each independently rated and ranked above.
How are these ranked?: By our independent score, currently based on FDA regulatory recall-safety data (the methodology blends additional sources as they come online). See the How we rate page.