Which calcitonin gene-related peptide receptor antagonist drugs treat migraine with aura?

pharmaranks lists 2 Calcitonin Gene-related Peptide Receptor Antagonist products used for migraine with aura, per NIH RxClass drug-classification data — each independently rated and ranked above.

How are these ranked?

By our independent score, currently based on FDA regulatory recall-safety data (the methodology blends additional sources as they come online). See the How we rate page.

Best Calcitonin Gene-related Peptide Receptor Antagonist for migraine with aura

Top-rated pick: Ubrelvy — pharmaranks score 72/100, the highest of the 2 Calcitonin Gene-related Peptide Receptor Antagonist drugs used for migraine with aura, ranked by our independent FDA recall-safety score. Compare them with all treatments for migraine with aura or the full Calcitonin Gene-related Peptide Receptor Antagonist class. Not medical advice — always consult a professional.

Quick answer: Of the 2 calcitonin gene-related peptide receptor antagonist drugs we rate for migraine with aura, none are yet flagged as generics in our price data, and most are tablet. Our ranking reflects each drug’s FDA recall-safety record — not clinical effectiveness for migraine with aura; the right choice depends on your situation, so confirm it with your prescriber.

Rated against independent regulatory sources·Last updated August 17, 2026·How we rate

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Top calcitonin gene-related peptide receptor antagonist for migraine with aura: 1. Ubrelvy · 2. Zavzpret

Best-rated Calcitonin Gene-related Peptide Receptor Antagonist for migraine with aura, ranked by pharmaranks score
#	Drug	Rating	Type	Form	Generic?	Pharmacy pays
1	Ubrelvy	72/100	Prescription	Tablet	No data	—	View →
2	Zavzpret	64/100	Prescription	Spray/Inhaler	No data	—	View →

Full ranking · 2 drugs

ubrelvy

PrescriptionFDA-sourced

72/100

Ubrelvy (Ubrogepant) is a calcitonin gene-related peptide receptor antagonist used to treat Migraine Disorders, Migraine with Aura, Migraine Without Aura.

(6 data points)

calcitonin gene-related peptide receptor antagonistmigraine disordersmigraine with aura

Price varies

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zavzpret

PrescriptionFDA-sourced

64/100

Zavzpret (Zavegepant Hydrochloride) is a calcitonin gene-related peptide receptor antagonist used to treat Migraine with Aura, Migraine Without Aura.

(61 data points)

calcitonin gene-related peptide receptor antagonistmigraine with auramigraine without aura

Price varies

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Frequently asked

What is the best calcitonin gene-related peptide receptor antagonist for migraine with aura?: By our independent recall-safety rating — not an efficacy measure — ubrelvy ranks highest among Calcitonin Gene-related Peptide Receptor Antagonist drugs used for migraine with aura. Always consult a professional.
Which calcitonin gene-related peptide receptor antagonist drugs treat migraine with aura?: pharmaranks lists 2 Calcitonin Gene-related Peptide Receptor Antagonist products used for migraine with aura, per NIH RxClass drug-classification data — each independently rated and ranked above.
How are these ranked?: By our independent score, currently based on FDA regulatory recall-safety data (the methodology blends additional sources as they come online). See the How we rate page.