Question 1

What is ofloxacin?

Accepted Answer

OCUFLOX ® (ofloxacin ophthalmic solution) 0.3% is a sterile ophthalmic solution. It is a fluorinated carboxyquinolone anti-infective for topical ophthalmic use. Chemical Name: (±)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7 H -pyrido[1,2,3- de ]-1,4-benzoxazine-6-carboxylic acid. Contains: Active: ofloxacin 0.3% (3 mg/mL). Preservative: benzalkonium chloride (0.005%). Inactives : sodium chloride and purified water. May also contain hydrochloric acid and/or sodium hydroxide to adjust pH. OCUFLOX ® solution is unbuffered and formulated with a pH of 6.4 (range - 6.0 to 6.8). It has an osmolality of 300 mOsm/kg. Ofloxacin is a fluorinated 4-quinolone which differs from other fluorinated 4-quinolones in that there is a six member (pyridobenzoxazine) ring from positions 1 to 8 of the basic ring structure. (±)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid.

Question 2

What kind of drug is ofloxacin?

Accepted Answer

The FDA classifies ofloxacin as a quinolone antimicrobial. If you are checking whether it is safe to combine with something else, the class is what matters — two drugs from the same class usually should not be stacked.

Question 3

Can you take ofloxacin with other medicines?

Accepted Answer

It depends on the medicine. We check it against the FDA labels rather than guessing: our interaction checker searches each drug's own label for the other and quotes what it says, naming the section it came from. Run ofloxacin against whatever else you take — and remember that a label not naming a drug is not the same as that combination being safe.

Question 4

What brand names is ofloxacin sold under?

Accepted Answer

We track 6 ofloxacin-containing products in the U.S.: Ocuflox, Ofloxacin, Floxin, Floxin in Dextrose 5%, Floxin in Dextrose 5% in Plastic Container and Floxin Otic. They are the same active ingredient; they differ in form, manufacturer, price and FDA recall record.

Question 5

What forms does ofloxacin come in?

Accepted Answer

Across the brands we track, ofloxacin is currently marketed as drops, solution, tablet and injectable, per the FDA's National Drug Code Directory. Each form is dosed differently — follow the label for the exact product you were prescribed.

Question 6

Is there a generic ofloxacin?

Accepted Answer

Yes. Our catalog lists 1 generic ofloxacin product alongside the brand versions. A generic has the same active ingredient and must meet the FDA's bioequivalence standard; it usually costs less. Ask your pharmacist which one your plan covers.

Question 7

Has ofloxacin been recalled?

Accepted Answer

The FDA's Enforcement database lists at least 5 recall records whose product description mentions ofloxacin. The most recent: Ciprofloxacin 0.3% and Dexamethasone 0.1% Otic Suspension Rx Only (Aug 13, 2025). A recall applies to specific lots, not to the drug as a whole — check the record for the affected lot numbers.

#	Drug	Rating	Type	Form	Generic?	Typical price
1	Ocuflox	70/100	Prescription	Drops	Generic	$1	View →
2	Ofloxacin	64/100	Prescription	Solution	Generic

Imprint	Strength	Colour	Shape	Maker
RDY;280	500 mg	orange	capsule	—
RDY;281	750 mg	yellow	capsule	—
ZC55	250 mg	white	capsule	—
I;18	750 mg	white	capsule	—
I;26	500 mg	orange	capsule	—
L54	500 mg

Ofloxacin: uses, dosing, side effects & brands

Key facts

How ofloxacin is dosed

Ofloxacin side effects

Who shouldn’t take ofloxacin

Ofloxacin drug interactions

Ofloxacin and food

Every ofloxacin product we track (6)

What ofloxacin pills look like

Combination products containing ofloxacin

Ofloxacin recalls

Frequently asked questions