Enalapril maleate oral solution is the maleate salt of enalapril, the ethyl ester prodrug of a long-acting angiotensin-converting enzyme inhibitor, enalaprilat. Enalapril maleate is chemically described as (S)-1-[N-[1-(ethoxycarbonyl)-3-phenylpropyl]-L-alanyl]-L-proline, (Z)-2-butenedioate salt (1:1). Its empirical formula is C 20 H 28 N 2 O 5 •C 4 H 4 O 4 , and its structural formula is: Enalapril maleate is a white to off-white, crystalline powder with a molecular weight of 492.52. It is sparingly soluble in water, soluble in ethanol, and freely soluble in methanol. Enalapril maleate oral solution is a ready-to-use oral solution. Each 1 mL contains 1 mg of enalapril maleate, USP equivalent to 0.764 mg of enalapril. Inactive ingredients include citric acid, mixed berry flavor, purified water, sodium benzoate, sodium citrate, and sucralose. It may also contain hydrochloric acid or sodium hydroxide for pH adjustment. Enalapril maleate oral solution is clear and colorless. Structural Formula

What kind of drug is enalapril?

The FDA classifies enalapril as an angiotensin converting enzyme inhibitor. If you are checking whether it is safe to combine with something else, the class is what matters — two drugs from the same class usually should not be stacked.

Can you take enalapril with other medicines?

It depends on the medicine. We check it against the FDA labels rather than guessing: our interaction checker searches each drug's own label for the other and quotes what it says, naming the section it came from. Run enalapril against whatever else you take — and remember that a label not naming a drug is not the same as that combination being safe.

What brand names is enalapril sold under?

We track 4 enalapril-containing products in the U.S.: Epaned, Epaned Kit, Enalapril Maleate and Vasotec. They are the same active ingredient; they differ in form, manufacturer, price and FDA recall record.

What forms does enalapril come in?

Across the brands we track, enalapril is currently marketed as solution and tablet, per the FDA's National Drug Code Directory. Each form is dosed differently — follow the label for the exact product you were prescribed.

Is there a generic enalapril?

Yes. Our catalog lists 1 generic enalapril product alongside the brand versions. A generic has the same active ingredient and must meet the FDA's bioequivalence standard; it usually costs less. Ask your pharmacist which one your plan covers.

Has enalapril been recalled?

The FDA's Enforcement database lists 1 recall record whose product description mentions enalapril. The most recent: Enalapril Maleate Tablets (Apr 23, 2026). A recall applies to specific lots, not to the drug as a whole — check the record for the affected lot numbers.

Enalapril: uses, dosing, side effects & brands

Enalapril is an angiotensin converting enzyme inhibitor sold in the U.S. under 4 brand and generic names, for rheumatoid arthritis, bartter syndrome and diabetic nephropathies. Below: what the FDA label says, every product that contains it, what the pills look like, and its recall record.

By the pharmaranks editorial teamReviewed against the FDA (openFDA label, NDC Directory & Enforcement) sourcesHow we research

Key facts

Drug class: Angiotensin Converting Enzyme Inhibitor
Treats: Rheumatoid Arthritis, Bartter Syndrome and Diabetic Nephropathies
Available as: Solution · Tablet
Sold as: 4 products — Epaned, Epaned Kit and Enalapril Maleate, and others
Prescription?: Prescription only
Generic available?: Yes
Typical price: about $0 for a 30-count supply
Boxed warning: Boxed warning

How enalapril is dosed

From the FDA label for Epaned (application NDA208686). Other enalapril products — different forms, different strengths — are dosed differently. Follow the label for the one you were prescribed.

Hypertension Adult: recommended initial dose is 5 mg once daily. Maximum dose is 40 mg daily ( 2.1 ). Pediatrics: recommended starting dose is 0.08 mg/kg (up to 5 mg) once daily ( 2.1 ). Heart Failure: Initiate at 2.5 mg twice daily. Titrate up to 20 mg twice daily as tolerated ( 2.2 ). Asymptomatic Left Ventricular Dysfunction: Initiate at 2.5 mg twice daily. Titrate up to 10 mg twice daily ( 2.3 ). Enalapril maleate oral solution is a ready-to-use solution intended for oral use only. 2.1 Hypertension Adults :The recommended initial dose in adults is 5 mg taken orally once a day. Titrate upward to maximum of 40 mg daily as needed to help achieve blood pressure goals. The dose may be divided and administered twice daily if the antihypertensive effect diminishes at the end of the dosing interval. Use with diuretics: If additional blood pressure reduction is needed, enalapril maleate may be administered with a low dose of diuretic. The recommended initial dose in patients taking diuretics is 2.5 mg daily. Dosage Adjustment for Renal Impairment: See table below. The dosage may be titrated upward as needed to a maximum of 40 mg daily. Renal Status Creatinine-Clearance mL/min Initial Dose mg/day Normal or Mild Impairment of Renal Function >30 mL/min 5 mg Moderate to Severe Impairment ≤30 mL/min 2.5 mg Dialysis Patients [See Warnings and Precautions ( 5.2)] . Should be taken after…

Enalapril side effects

The following adverse reactions are described elsewhere: Angioedema [see Warnings and Precautions ( 5.2 )] Hypotension [see Warnings and Precautions ( 5.3 )] Hepatic failure [see Warnings and Precautions ( 5.4 )] Renal impairment [see Warnings and Precautions ( 5.5 )] Hyperkalemia [see Warnings and Precautions ( 5.6 )] The most common adverse reaction for patients treated for hypertension (≥3%) was fatigue ( 6.1 ). The most common adverse reactions for patients treated for heart failure (>6%) were hypotension and dizziness ( 6.1 ). To report SUSPECTED ADVERSE REACTIONS, contact Wilshire Pharmaceuticals, Inc. at 1-877-495-6856 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch. 6.1 Clinical Trials Experience Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in clinical practice. Enalapril has been evaluated for safety in more than 10,000 patients, including over 1,000 patients treated for one year or more. In clinical trials, discontinuation of therapy for clinical adverse experiences was required in 3.3% of patients with hypertension and in 5.7% of patients with heart failure. Hypertension Adverse reactions (where rate on enalapril exceeds the rate on placebo by at least 0.2%)…

Enalapril and food

Potassium-rich foods & salt substitutes
Don't use potassium-based salt substitutes unless your clinician approves, and ask before taking potassium supplements. Your clinician may check your potassium level with blood tests.
Lisinopril (an ACE inhibitor) — MedlinePlus (U.S. National Library of Medicine) ↗

Every enalapril product we track (4)

Same active ingredient — different manufacturer, form, price and FDA recall record. That last one is what our independent score measures.

Enalapril products
#	Drug	Rating	Type	Form	Generic?	Typical price
1	Epaned Boxed warning	72/100	Prescription	Solution	Generic	$0	View →
2	Epaned Kit

What enalapril pills look like

Imprint codes, colour and shape from the FDA’s labelling data. Match the imprint on your pill — or search any imprint.

Enalapril pill imprints
Imprint	Strength	Colour	Shape	Maker
T4	5 mg / 12.5 mg	white	oval	—
T;3	10 mg / 25 mg	pink	oval	—
VASE;10;25	10 mg / 25 mg	red	oval	—
C133	5 mg / 12.5 mg	white	round	—
C134	10 mg / 25 mg	white	round	—
T3	10 mg / 25 mg

Combination products containing enalapril

A combination is a different drug — different dosing, different warnings. It is listed here so you can find it, not so you can substitute it.

Enalapril recalls

From the FDA Enforcement database. A recall covers specific lots — not the drug as a whole.

Enalapril Maleate Tablets
Failed Impurities/Degradation Specifications:Out of specification result occurred in Organic Impurities Test
JB Chemicals and Pharmaceuticals Ltd · Apr 23, 2026

Frequently asked questions

What is enalapril?: Enalapril maleate oral solution is the maleate salt of enalapril, the ethyl ester prodrug of a long-acting angiotensin-converting enzyme inhibitor, enalaprilat. Enalapril maleate is chemically described as (S)-1-[N-[1-(ethoxycarbonyl)-3-phenylpropyl]-L-alanyl]-L-proline, (Z)-2-butenedioate salt (1:1). Its empirical formula is C 20 H 28 N 2 O 5 •C 4 H 4 O 4 , and its structural formula is: Enalapril maleate is a white to off-white, crystalline powder with a molecular weight of 492.52. It is sparingly soluble in water, soluble in ethanol, and freely soluble in methanol. Enalapril maleate oral solution is a ready-to-use oral solution. Each 1 mL contains 1 mg of enalapril maleate, USP equivalent to 0.764 mg of enalapril. Inactive ingredients include citric acid, mixed berry flavor, purified water, sodium benzoate, sodium citrate, and sucralose. It may also contain hydrochloric acid or sodium hydroxide for pH adjustment. Enalapril maleate oral solution is clear and colorless. Structural Formula
What kind of drug is enalapril?: The FDA classifies enalapril as an angiotensin converting enzyme inhibitor. If you are checking whether it is safe to combine with something else, the class is what matters — two drugs from the same class usually should not be stacked.
Can you take enalapril with other medicines?: It depends on the medicine. We check it against the FDA labels rather than guessing: our interaction checker searches each drug's own label for the other and quotes what it says, naming the section it came from. Run enalapril against whatever else you take — and remember that a label not naming a drug is not the same as that combination being safe.
What brand names is enalapril sold under?: We track 4 enalapril-containing products in the U.S.: Epaned, Epaned Kit, Enalapril Maleate and Vasotec. They are the same active ingredient; they differ in form, manufacturer, price and FDA recall record.
What forms does enalapril come in?: Across the brands we track, enalapril is currently marketed as solution and tablet, per the FDA's National Drug Code Directory. Each form is dosed differently — follow the label for the exact product you were prescribed.

Sources: FDA openFDA drug label, National Drug Code Directory, and Enforcement (recall) database. This page reproduces public FDA data and is not medical advice. Dosing is set by your prescriber.