What is the difference between Adderall XR and Annovera?

Adderall XR contains Dextroamphetamine Sulfate, Dextroamphetamine Saccharate, Amphetamine Sulfate and Amphetamine Aspartate, while Annovera contains Ethinyl Estradiol and Segesterone Acetate — they have different active ingredients.

ADDERALL XR vs ANNOVERA

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated July 13, 2026·How we rate

Possible drug interaction. ADDERALL XR and ANNOVERA are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ADDERALL XR	ANNOVERA
Rating	New	72/100
Pharmacy pays	—	—
Type	RX	RX
Active ingredient	DEXTROAMPHETAMINE SULFATE, DEXTROAMPHETAMINE SACCHARATE, AMPHETAMINE SULFATE AND AMPHETAMINE ASPARTATE	ETHINYL ESTRADIOL AND SEGESTERONE ACETATE
Manufacturer	Takeda Pharms USA	Mayne Pharma
Dosage forms	Capsule, extended release	Ring
Drug class	—	—
Boxed warning	Boxed warning	Boxed warning
Half-life	about 10 to 11 hours for d-amphetamine (range 9.8 to 11 hours) and about 12 to 14 hours for l-amphetamine (range 11.5 to 13.8 hours) in healthy adults	—

adderall xr annovera

Rating

New

72/100

Pharmacy pays

—

Type

Active ingredient

DEXTROAMPHETAMINE SULFATE, DEXTROAMPHETAMINE SACCHARATE, AMPHETAMINE SULFATE AND AMPHETAMINE ASPARTATE

ETHINYL ESTRADIOL AND SEGESTERONE ACETATE

Manufacturer

Takeda Pharms USA

Mayne Pharma

Dosage forms

Capsule, extended release

Ring

Drug class

—

Boxed warning

Half-life

about 10 to 11 hours for d-amphetamine (range 9.8 to 11 hours) and about 12 to 14 hours for l-amphetamine (range 11.5 to 13.8 hours) in healthy adults

—

Frequently asked questions

What is the difference between Adderall XR and Annovera?: Adderall XR contains Dextroamphetamine Sulfate, Dextroamphetamine Saccharate, Amphetamine Sulfate and Amphetamine Aspartate, while Annovera contains Ethinyl Estradiol and Segesterone Acetate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.