What is the difference between Adderall XR and Anagrelide Hydrochloride?

Adderall XR contains Dextroamphetamine Sulfate, Dextroamphetamine Saccharate, Amphetamine Sulfate and Amphetamine Aspartate, while Anagrelide Hydrochloride contains Anagrelide Hydrochloride — they have different active ingredients.

ADDERALL XR vs ANAGRELIDE HYDROCHLORIDE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated July 13, 2026·How we rate

Possible drug interaction. ADDERALL XR and ANAGRELIDE HYDROCHLORIDE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ADDERALL XR	ANAGRELIDE HYDROCHLORIDE
Rating	New	72/100
Pharmacy pays	—	~$32.95 /30
Type	RX	RX
Active ingredient	DEXTROAMPHETAMINE SULFATE, DEXTROAMPHETAMINE SACCHARATE, AMPHETAMINE SULFATE AND AMPHETAMINE ASPARTATE	ANAGRELIDE HYDROCHLORIDE
Manufacturer	Takeda Pharms USA	Novitium Pharma
Dosage forms	Capsule, extended release	Capsule
Drug class	—	Platelet-Reducing Agent
Boxed warning	Boxed warning	None
Half-life	about 10 to 11 hours for d-amphetamine (range 9.8 to 11 hours) and about 12 to 14 hours for l-amphetamine (range 11.5 to 13.8 hours) in healthy adults	about 1.5 hours
Treats	—	Polycythemia Vera, Thrombocytosis

adderall xr anagrelide hydrochloride

Rating

New

72/100

Pharmacy pays

—

~$32.95 /30

Type

Active ingredient

DEXTROAMPHETAMINE SULFATE, DEXTROAMPHETAMINE SACCHARATE, AMPHETAMINE SULFATE AND AMPHETAMINE ASPARTATE

ANAGRELIDE HYDROCHLORIDE

Manufacturer

Takeda Pharms USA

Novitium Pharma

Dosage forms

Capsule, extended release

Capsule

Drug class

—

Platelet-Reducing Agent

Boxed warning

None

Half-life

about 10 to 11 hours for d-amphetamine (range 9.8 to 11 hours) and about 12 to 14 hours for l-amphetamine (range 11.5 to 13.8 hours) in healthy adults

about 1.5 hours

Treats

—

Polycythemia Vera, Thrombocytosis

Frequently asked questions

What is the difference between Adderall XR and Anagrelide Hydrochloride?: Adderall XR contains Dextroamphetamine Sulfate, Dextroamphetamine Saccharate, Amphetamine Sulfate and Amphetamine Aspartate, while Anagrelide Hydrochloride contains Anagrelide Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.