Trihexyphenidyl: uses, dosing, side effects & brands
Trihexyphenidyl is a medicine sold in the U.S. under 2 brand and generic names. Below: what the FDA label says, every product that contains it, what the pills look like, and its recall record.
Key facts
- Available as
- Tablet · Capsule, extended release · Elixir
- Sold as
- 2 products — Trihexyphenidyl Hydrochloride and Artane
- Prescription?
- Prescription only
- Generic available?
- Yes
- What the pharmacy pays
- about $3 for a 30-count supply — not your price
Every trihexyphenidyl product we track (2)
Same active ingredient — different manufacturer, form, price and FDA recall record. That last one is what our independent score measures.
| # | Drug | Rating | Type | Form | Generic? | Pharmacy pays | |
|---|---|---|---|---|---|---|---|
| 1 | 72/100 | Prescription | Tablet | Generic | $3 | View → | |
| 2 | Not yet rated | Prescription | Tablet | Generic | $3 | View → |
What trihexyphenidyl pills look like
Imprint codes, colour and shape from the FDA’s labelling data. Match the imprint on your pill — or search any imprint.
| Imprint | Strength | Colour | Shape | Maker |
|---|---|---|---|---|
| 212;N | 2 mg | white | round | — |
| 211;N | 5 mg | white | round | — |
| DAN;DAN;5337 | 5 mg | white | round | — |
| DAN;DAN;5335 | 2 mg | white | round | — |
| DAN;DAN;5337 | 5 mg | white | round | — |
Can you crush or split trihexyphenidyl?
The trihexyphenidyl labels that address it permit crushing or splitting in the terms they state — quoted per product, because the instruction belongs to the form.
What each trihexyphenidyl label says about crushing, splitting and chewingHow long trihexyphenidyl keeps
No trihexyphenidyl label we read sets a separate limit for after opening, but they do specify how it must be stored — and the stability behind any date assumes those conditions.
Trihexyphenidyl and breastfeeding
From LactMed, the US National Library of Medicine’s Drugs and Lactation Database — quoted, not rewritten.
Full LactMed record for trihexyphenidyl: levels in milk, effects in breastfed infants, and the drugs it would consider insteadLimited information indicates that maternal doses of trihexyphenidyl up to 4 mg daily together with haloperidol or risperidone did not produce any adverse effects in breastfed infants. Long-term use of trihexyphenidyl might reduce milk production or milk letdown, but a single dose is not likely to interfere with breastfeeding. The prolactin elevating effect of concurrent antipsychotic agents might counteract any prolactin lowering effect of trihexyphenidyl. During long-term use, observe for signs of decreased lactation (e.g., infant insatiety and poor weight gain).
National Institute of Child Health and Human Development, record revised February 15, 2024. LactMed states its information is not a substitute for professional judgement.
What people report to the FDA about trihexyphenidyl
The FDA Adverse Event Reporting System (FAERS) collects reports from patients and clinicians. It holds 1,109 reports naming trihexyphenidyl, and the FDA flagged 91% of those reports as serious. The effects reported most often — leaving out reports about overdose, misuse or the condition being treated, which dominate the raw list for common medicines:
- nausea58 reports
- fall54 reports
- coma53 reports
- confusional state45 reports
- ischaemic stroke42 reports
- respiratory distress42 reports
- respiratory failure41 reports
- somnolence40 reports
Read these as a signal, not a rate. A report does not mean trihexyphenidyl caused the effect — anyone can file one, and many describe people taking several medicines for several conditions. Crucially there is no denominator: FAERS does not record how many people took the drug, so these counts cannot be turned into “X% of patients” — a bigger number often just means a more widely used or more talked-about drug. Duplicates exist, and publicity drives reporting. For what is actually established, read the FDA label.
Source: openFDA drug/event (FAERS), retrieved August 26, 2026.
Related calculators
Frequently asked questions
Can you take trihexyphenidyl with other medicines?
It depends on the medicine. We check it against the FDA labels rather than guessing: our interaction checker searches each drug's own label for the other and quotes what it says, naming the section it came from. Run trihexyphenidyl against whatever else you take — and remember that a label not naming a drug is not the same as that combination being safe.
What brand names is trihexyphenidyl sold under?
We track 2 trihexyphenidyl-containing products in the U.S.: Trihexyphenidyl Hydrochloride and Artane. They are the same active ingredient; they differ in form, manufacturer, price and FDA recall record.
What forms does trihexyphenidyl come in?
Across the brands we track, trihexyphenidyl is currently marketed as tablet, capsule, extended release and elixir, per the FDA's National Drug Code Directory. Each form is dosed differently — follow the label for the exact product you were prescribed.
Is there a generic trihexyphenidyl?
Yes. Our catalog lists 1 generic trihexyphenidyl product alongside the brand versions. A generic has the same active ingredient and must meet the FDA's bioequivalence standard; it usually costs less. Ask your pharmacist which one your plan covers.
Cite this page
- APA
- pharmaranks. (2026, July 24). Trihexyphenidyl: uses, dosing, side effects & brands. https://pharmaranks.com/drugs/trihexyphenidyl
- MLA
- “Trihexyphenidyl: uses, dosing, side effects & brands.” pharmaranks, 24 July 2026, https://pharmaranks.com/drugs/trihexyphenidyl.
We summarise public FDA and NIH sources — for a clinical claim, cite the primary source we link to as well.
Sources: FDA openFDA drug label, National Drug Code Directory, and Enforcement (recall) database. This page reproduces public FDA data and is not medical advice. Dosing is set by your prescriber.
Read the full FDA label for trihexyphenidyl on DailyMed (NIH) ↗.