Thiotepa: uses, dosing, side effects & brands
Thiotepa is a medicine sold in the U.S. under 2 brand and generic names. Below: what the FDA label says, every product that contains it, what the pills look like, and its recall record.
Key facts
- Available as
- Injectable
- Sold as
- 2 products — Tepylute and Thioplex
- Prescription?
- Prescription only
- Generic available?
- Not in our catalog
Every thiotepa product we track (2)
Same active ingredient — different manufacturer, form, price and FDA recall record. That last one is what our independent score measures.
| # | Drug | Rating | Type | Form | Generic? | Pharmacy pays | |
|---|---|---|---|---|---|---|---|
| 1 | Not yet rated | Prescription | Injectable | No data | — | View → | |
| 2 | Not yet rated | Prescription | Injectable | No data | — | View → |
How long thiotepa keeps
The date on a sealed pack is not the only one: some thiotepa labels start a second clock once the product is opened or mixed, as short as 4 hours.
The in-use limits thiotepa labels print, quotedWhat people report to the FDA about thiotepa
The FDA Adverse Event Reporting System (FAERS) collects reports from patients and clinicians. It holds 9,347 reports naming thiotepa, and the FDA flagged 98% of those reports as serious. The effects reported most often — leaving out reports about overdose, misuse or the condition being treated, which dominate the raw list for common medicines:
- febrile neutropenia783 reports
- mucosal inflammation779 reports
- cytomegalovirus infection535 reports
- pyrexia497 reports
- acute graft versus host disease452 reports
- acute graft versus host disease in skin447 reports
- cytomegalovirus infection reactivation424 reports
- infection420 reports
Read these as a signal, not a rate. A report does not mean thiotepa caused the effect — anyone can file one, and many describe people taking several medicines for several conditions. Crucially there is no denominator: FAERS does not record how many people took the drug, so these counts cannot be turned into “X% of patients” — a bigger number often just means a more widely used or more talked-about drug. Duplicates exist, and publicity drives reporting. For what is actually established, read the FDA label.
Source: openFDA drug/event (FAERS), retrieved September 26, 2026.
Related calculators
Frequently asked questions
Can you take thiotepa with other medicines?
It depends on the medicine. We check it against the FDA labels rather than guessing: our interaction checker searches each drug's own label for the other and quotes what it says, naming the section it came from. Run thiotepa against whatever else you take — and remember that a label not naming a drug is not the same as that combination being safe.
What brand names is thiotepa sold under?
We track 2 thiotepa-containing products in the U.S.: Tepylute and Thioplex. They are the same active ingredient; they differ in form, manufacturer, price and FDA recall record.
What forms does thiotepa come in?
Across the brands we track, thiotepa is currently marketed as injectable, per the FDA's National Drug Code Directory. Each form is dosed differently — follow the label for the exact product you were prescribed.
Is there a generic thiotepa?
We do not currently list a generic-labelled thiotepa product. That does not always mean none exists — it means none appears under a generic name in the FDA data we track. Ask your pharmacist.
Cite this page
- APA
- pharmaranks. (2026, July 24). Thiotepa: uses, dosing, side effects & brands. https://pharmaranks.com/drugs/thiotepa
- MLA
- “Thiotepa: uses, dosing, side effects & brands.” pharmaranks, 24 July 2026, https://pharmaranks.com/drugs/thiotepa.
We summarise public FDA and NIH sources — for a clinical claim, cite the primary source we link to as well.
Sources: FDA openFDA drug label, National Drug Code Directory, and Enforcement (recall) database. This page reproduces public FDA data and is not medical advice. Dosing is set by your prescriber.
Read the full FDA label for thiotepa on DailyMed (NIH) ↗.