Solifenacin: uses, dosing, side effects & brands
Solifenacin is a medicine sold in the U.S. under 3 brand and generic names. Below: what the FDA label says, every product that contains it, what the pills look like, and its recall record.
Key facts
- Available as
- Tablet · Suspension
- Sold as
- 3 products — Solifenacin Succinate, Vesicare and Vesicare Ls
- Prescription?
- Prescription only
- Generic available?
- Yes
- Half-life
- about 45 to 68 hours
- What the pharmacy pays
- about $5 for a 30-count supply — not your price
Every solifenacin product we track (3)
Same active ingredient — different manufacturer, form, price and FDA recall record. That last one is what our independent score measures.
| # | Drug | Rating | Type | Form | Generic? | Pharmacy pays | |
|---|---|---|---|---|---|---|---|
| 1 | 72/100 | Prescription | Tablet | Generic | $5 | View → | |
| 2 | 72/100 | Prescription | Tablet | Generic | $5 | View → | |
| 3 | 72/100 | Prescription | Suspension | Generic | $5 | View → |
What solifenacin pills look like
Imprint codes, colour and shape from the FDA’s labelling data. Match the imprint on your pill — or search any imprint.
Solifenacin recalls
From the FDA Enforcement database. A recall covers specific lots — not the drug as a whole.
Can you crush or split solifenacin?
At least one solifenacinproduct is labelled to be swallowed whole — crushing an extended-release tablet releases the whole day’s dose at once. Which applies depends on the form you were given.
What each solifenacin label says about crushing, splitting and chewingSolifenacin and breastfeeding
From LactMed, the US National Library of Medicine’s Drugs and Lactation Database — quoted, not rewritten.
Full LactMed record for solifenacin: levels in milk, effects in breastfed infants, and the drugs it would consider insteadBecause there is no published experience with solifenacin during breastfeeding and it has a long half-life averaging 55 hours, an alternate drug may be preferred, especially while nursing a newborn or preterm infant. Long-term use of solifenacin might reduce milk production or milk letdown. During long-term use, observe the infant for signs of decreased milk production (e.g., insatiety, poor weight gain) and for anticholinergic symptoms (e.g., constipation, urinary retention, UTI, dry mouth).
National Institute of Child Health and Human Development, record revised April 19, 2021. LactMed states its information is not a substitute for professional judgement.
What people report to the FDA about solifenacin
The FDA Adverse Event Reporting System (FAERS) collects reports from patients and clinicians. It holds 2,140 reports naming solifenacin, and the FDA flagged 76% of those reports as serious. The effects reported most often — leaving out reports about overdose, misuse or the condition being treated, which dominate the raw list for common medicines:
- fatigue150 reports
- fall146 reports
- dizziness127 reports
- malaise105 reports
- diarrhoea100 reports
- nausea99 reports
- constipation98 reports
- headache98 reports
Read these as a signal, not a rate. A report does not mean solifenacin caused the effect — anyone can file one, and many describe people taking several medicines for several conditions. Crucially there is no denominator: FAERS does not record how many people took the drug, so these counts cannot be turned into “X% of patients” — a bigger number often just means a more widely used or more talked-about drug. Duplicates exist, and publicity drives reporting. For what is actually established, read the FDA label.
Source: openFDA drug/event (FAERS), retrieved September 26, 2026.
How long solifenacin stays in your system
The elimination half-life of solifenacin is about 45 to 68 hours. The label gives this range for solifenacin itself after chronic (repeat) dosing, so a dose change takes roughly a week to fully settle. The label names one pharmacologically active metabolite, 4R-hydroxy solifenacin, but states it occurs at low concentrations and is unlikely to contribute significantly to clinical activity — no half-life is given for it. Solifenacin is cleared mainly by CYP3A4 in the liver, so the half-life stretches in several groups: about 20 to 25% longer in adults 65 to 80 compared with adults 18 to 55; about 1.6-fold longer with severe kidney impairment (AUC 2.1-fold higher); and about 2-fold longer with moderate liver impairment. It has not been studied in severe liver impairment. Strong CYP3A4 inhibitors such as ketoconazole raise exposure about 2.7-fold. In the US solifenacin is sold as immediate-release tablets and an oral suspension; there is no extended-release form, so no ER-versus-IR difference applies.
Solifenacin Succinate Tablets — FDA Prescribing Information, Section 12.3 Pharmacokinetics (DailyMed) ↗Half-life is how long the body takes to clear half a dose. It is not the same as how long a drug test can detect it, and it varies with age, kidney and liver function.
Related calculators
Frequently asked questions
How long does solifenacin stay in your system?
The elimination half-life of solifenacin is about 45 to 68 hours — that is how long the body takes to clear half of a dose. The label gives this range for solifenacin itself after chronic (repeat) dosing, so a dose change takes roughly a week to fully settle. The label names one pharmacologically active metabolite, 4R-hydroxy solifenacin, but states it occurs at low concentrations and is unlikely to contribute significantly to clinical activity — no half-life is given for it. Solifenacin is cleared mainly by CYP3A4 in the liver, so the half-life stretches in several groups: about 20 to 25% longer in adults 65 to 80 compared with adults 18 to 55; about 1.6-fold longer with severe kidney impairment (AUC 2.1-fold higher); and about 2-fold longer with moderate liver impairment. It has not been studied in severe liver impairment. Strong CYP3A4 inhibitors such as ketoconazole raise exposure about 2.7-fold. In the US solifenacin is sold as immediate-release tablets and an oral suspension; there is no extended-release form, so no ER-versus-IR difference applies. Half-life is not the same as how long a drug test can detect the drug, and it varies with age, kidney and liver function.
Can you take solifenacin with other medicines?
It depends on the medicine. We check it against the FDA labels rather than guessing: our interaction checker searches each drug's own label for the other and quotes what it says, naming the section it came from. Run solifenacin against whatever else you take — and remember that a label not naming a drug is not the same as that combination being safe.
What brand names is solifenacin sold under?
We track 3 solifenacin-containing products in the U.S.: Solifenacin Succinate, Vesicare and Vesicare Ls. They are the same active ingredient; they differ in form, manufacturer, price and FDA recall record.
What forms does solifenacin come in?
Across the brands we track, solifenacin is currently marketed as tablet and suspension, per the FDA's National Drug Code Directory. Each form is dosed differently — follow the label for the exact product you were prescribed.
Is there a generic solifenacin?
Yes. Our catalog lists 1 generic solifenacin product alongside the brand versions. A generic has the same active ingredient and must meet the FDA's bioequivalence standard; it usually costs less. Ask your pharmacist which one your plan covers.
Has solifenacin been recalled?
The FDA's Enforcement database lists 2 recall records whose product description mentions solifenacin. The most recent: Solifenacin Succinate Tablets 10MG (Mar 13, 2025). A recall applies to specific lots, not to the drug as a whole — check the record for the affected lot numbers.
Cite this page
- APA
- pharmaranks. (2026, July 24). Solifenacin: uses, dosing, side effects & brands. https://pharmaranks.com/drugs/solifenacin
- MLA
- “Solifenacin: uses, dosing, side effects & brands.” pharmaranks, 24 July 2026, https://pharmaranks.com/drugs/solifenacin.
We summarise public FDA and NIH sources — for a clinical claim, cite the primary source we link to as well.
Sources: FDA openFDA drug label, National Drug Code Directory, and Enforcement (recall) database. This page reproduces public FDA data and is not medical advice. Dosing is set by your prescriber.
Read the full FDA label for solifenacin on DailyMed (NIH) ↗.