Rufinamide is a triazole derivative structurally unrelated to currently marketed antiepileptic drugs (AEDs). Rufinamide has the chemical name 1-[(2,6-difluorophenyl)methyl]-1 H -1,2,3-triazole-4 carboxamide. It has a molecular formula of C 10 H 8 F 2 N 4 O and a molecular weight of 238.2. The drug substance is a white to off-white crystalline powder. Rufinamide USP is slightly soluble in tetrahydrofuran and in methanol; very slightly soluble in alcohol and in acetonitrile; practically insoluble in water. Rufinamide is also available for oral administration as a liquid containing rufinamide at a concentration of 40 mg/mL. Inactive ingredients include citric acid anhydrous, hydroxyethylcellulose, methylparaben, microcrystalline cellulose and carboxymethylcellulose sodium, noncrystallizing sorbitol solution, orange flavor (which contains dl-alpha-tocopherols and natural & artificial flavors), poloxamer 188, potassium sorbate, propylene glycol, propylparaben, purified water, and simethicone emulsion. structure

Can you take rufinamide with other medicines?

It depends on the medicine. We check it against the FDA labels rather than guessing: our interaction checker searches each drug's own label for the other and quotes what it says, naming the section it came from. Run rufinamide against whatever else you take — and remember that a label not naming a drug is not the same as that combination being safe.

What brand names is rufinamide sold under?

We track 2 rufinamide-containing products in the U.S.: Rufinamide and Banzel. They are the same active ingredient; they differ in form, manufacturer, price and FDA recall record.

What forms does rufinamide come in?

Across the brands we track, rufinamide is currently marketed as suspension and tablet, per the FDA's National Drug Code Directory. Each form is dosed differently — follow the label for the exact product you were prescribed.

Is there a generic rufinamide?

Yes. Our catalog lists 1 generic rufinamide product alongside the brand versions. A generic has the same active ingredient and must meet the FDA's bioequivalence standard; it usually costs less. Ask your pharmacist which one your plan covers.

Has rufinamide been recalled?

The FDA's Enforcement database lists 1 recall record whose product description mentions rufinamide. The most recent: Rufinamide Tablets 200mg (Mar 13, 2025). A recall applies to specific lots, not to the drug as a whole — check the record for the affected lot numbers.

Rufinamide: uses, dosing, side effects & brands

Rufinamide is a medicine sold in the U.S. under 2 brand and generic names, for seizures. Below: what the FDA label says, every product that contains it, what the pills look like, and its recall record.

By the pharmaranks editorial teamReviewed against the FDA (openFDA label, NDC Directory & Enforcement) sourcesHow we research

Key facts

Treats: Seizures
Available as: Suspension · Tablet
Sold as: 2 products — Rufinamide and Banzel
Prescription?: Prescription only
Generic available?: Yes
Typical price: about $28 for a 30-count supply

How rufinamide is dosed

From the FDA label for Rufinamide (application ANDA216549). Other rufinamide products — different forms, different strengths — are dosed differently. Follow the label for the one you were prescribed.

Rufinamide oral suspension should be given with food. ( 2.2 ) Measure oral suspension using provided adapter and dosing syringe ( 2.2 ) Pediatric patients 1 year and older: Starting daily dose: 10 mg/kg per day in two equally divided doses ( 2.1 ) Increase by 10 mg/kg increments every other day to maximum dose of 45 mg/kg per day, not to exceed 3200 mg per day, in two divided doses ( 2.1 ) Adults: Starting daily dose: 400 mg to 800 mg per day in two equally divided doses ( 2.1 ) Increase by 400 mg to 800 mg every other day until a maximum dose of 3200 mg per day, in two divided doses, is reached ( 2.1 ) 2.1 Dosage Information Pediatric patients (1 year to less than 17 years) The recommended starting daily dose of rufinamide oral suspension in pediatric patients with Lennox-Gastaut Syndrome is approximately 10 mg/kg administered in two equally divided doses. The dose should be increased by approximately 10 mg/kg increments every other day until a maximum daily dose of 45 mg/kg, not to exceed 3200 mg, administered in two equally divided doses, is reached. It is not known whether doses lower than the target doses are effective. Adults (17 years and older) The recommended starting daily dose of rufinamide oral suspension in adults with Lennox-Gastaut Syndrome is 400 mg to 800 mg per day administered in two equally divided doses. The dose should be increased by 400 mg to 800 mg…

Rufinamide side effects

The following serious adverse reactions are described below and elsewhere in the labeling: Suicidal Behavior and Ideation [see Warnings and Precautions (5.1) ] Central Nervous System Reactions [see Warnings and Precautions (5.2) ] QT Shortening [see Warnings and Precautions (5.3) ] Multi-Organ Hypersensitivity/Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) [see Warnings and Precautions (5.4) ] Leukopenia [see Warnings and Precautions (5.7) ] Most common adverse reactions (≥ 10% and greater than placebo) were headache, dizziness, fatigue, somnolence, and nausea ( 6.1 ) To report SUSPECTED ADVERSE REACTIONS, contact Aurobindo Pharma USA, Inc. at 1-866-850-2876 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch. 6.1 Clinical Trials Experience Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice. Adverse Reactions in Adult and Pediatric Patients ages 3 to 17 years of age In the pooled, double-blind, adjunctive therapy studies in adult and pediatric patients ages 3 to 17 years of age, the most common (≥10%) adverse reactions in rufinamide-treated patients, in all doses studied (200 to 3200 mg per day) with a higher frequency than in patients on placebo were:…

Every rufinamide product we track (2)

Same active ingredient — different manufacturer, form, price and FDA recall record. That last one is what our independent score measures.

Rufinamide products
#	Drug	Rating	Type	Form	Generic?	Typical price
1	Rufinamide	64/100	Prescription	Suspension	Generic	$28	View →
2	Banzel	Not yet rated	Prescription	Suspension	Generic	$28

What rufinamide pills look like

Imprint codes, colour and shape from the FDA’s labelling data. Match the imprint on your pill — or search any imprint.

Rufinamide pill imprints
Imprint	Strength	Colour	Shape	Maker
G;713	200 mg	pink	oval	—
G;714	400 mg	pink	oval	—
LU;P71	100 mg	pink	oval	—
LU;P72	200 mg	pink	oval	—
LU;P73	400 mg	pink	oval	—

Rufinamide recalls

From the FDA Enforcement database. A recall covers specific lots — not the drug as a whole.

Rufinamide Tablets 200mg
CGMP Deviations
Glenmark Pharmaceuticals Inc., USA · Mar 13, 2025

Frequently asked questions

What is rufinamide?: Rufinamide is a triazole derivative structurally unrelated to currently marketed antiepileptic drugs (AEDs). Rufinamide has the chemical name 1-[(2,6-difluorophenyl)methyl]-1 H -1,2,3-triazole-4 carboxamide. It has a molecular formula of C 10 H 8 F 2 N 4 O and a molecular weight of 238.2. The drug substance is a white to off-white crystalline powder. Rufinamide USP is slightly soluble in tetrahydrofuran and in methanol; very slightly soluble in alcohol and in acetonitrile; practically insoluble in water. Rufinamide is also available for oral administration as a liquid containing rufinamide at a concentration of 40 mg/mL. Inactive ingredients include citric acid anhydrous, hydroxyethylcellulose, methylparaben, microcrystalline cellulose and carboxymethylcellulose sodium, noncrystallizing sorbitol solution, orange flavor (which contains dl-alpha-tocopherols and natural & artificial flavors), poloxamer 188, potassium sorbate, propylene glycol, propylparaben, purified water, and simethicone emulsion. structure
Can you take rufinamide with other medicines?: It depends on the medicine. We check it against the FDA labels rather than guessing: our interaction checker searches each drug's own label for the other and quotes what it says, naming the section it came from. Run rufinamide against whatever else you take — and remember that a label not naming a drug is not the same as that combination being safe.
What brand names is rufinamide sold under?: We track 2 rufinamide-containing products in the U.S.: Rufinamide and Banzel. They are the same active ingredient; they differ in form, manufacturer, price and FDA recall record.
What forms does rufinamide come in?: Across the brands we track, rufinamide is currently marketed as suspension and tablet, per the FDA's National Drug Code Directory. Each form is dosed differently — follow the label for the exact product you were prescribed.
Is there a generic rufinamide?: Yes. Our catalog lists 1 generic rufinamide product alongside the brand versions. A generic has the same active ingredient and must meet the FDA's bioequivalence standard; it usually costs less. Ask your pharmacist which one your plan covers.

Sources: FDA openFDA drug label, National Drug Code Directory, and Enforcement (recall) database. This page reproduces public FDA data and is not medical advice. Dosing is set by your prescriber.