Phendimetrazine: uses, dosing, side effects & brands

Key facts

Frequently asked questions

What is phendimetrazine?

Phendimetrazine tartrate, as the dextro isomer, has the chemical name of (2S,3S)-3,4-Dimethyl-2-phenylmorpholine L-(+)- tartrate (1:1). The structural formula is: Phendimetrazine tartrate is a white, odorless crystalline powder. It is freely soluble in water; sparingly soluble in warm alcohol, insoluble in chloroform, acetone, ether and benzene. Each white tablet, for oral administration, contains 35 mg of phendimetrazine tartrate. In addition, the following inactive ingredients are present: Colloidal Silicon Dioxide, Lactose Monohydrate, Microcrystalline Cellulose 102, Sodium Starch Glycolate and Stearic Acid. The yellow tablet also contains FD&C Yellow # 5 Aluminum Lake (15-17%). The blue tablet also contains FD&C Blue # 1 Aluminum Lake (11-13%). chemical structure

What kind of drug is phendimetrazine?

The FDA classifies phendimetrazine as a sympathomimetic amine anorectic. If you are checking whether it is safe to combine with something else, the class is what matters — two drugs from the same class usually should not be stacked.

Can you take phendimetrazine with other medicines?

It depends on the medicine. We check it against the FDA labels rather than guessing: our interaction checker searches each drug's own label for the other and quotes what it says, naming the section it came from. Run phendimetrazine against whatever else you take — and remember that a label not naming a drug is not the same as that combination being safe.

What brand names is phendimetrazine sold under?

We track 4 phendimetrazine-containing products in the U.S.: Phenazine, Phendimetrazine Tartrate, Plegine and X-Trozine. They are the same active ingredient; they differ in form, manufacturer, price and FDA recall record.

What forms does phendimetrazine come in?

Across the brands we track, phendimetrazine is currently marketed as capsule, capsule, extended release and tablet, per the FDA's National Drug Code Directory. Each form is dosed differently — follow the label for the exact product you were prescribed.