Orphenadrine is a muscle relaxant sold in the U.S. under 2 brand and generic names, for muscle cramp, muscle rigidity and myositis. Below: what the FDA label says, every product that contains it, what the pills look like, and its recall record.
From the FDA label for Disipal (application NDA010653). Other orphenadrine products — different forms, different strengths — are dosed differently. Follow the label for the one you were prescribed.
Adults-Two tablets per day; one in the morning and one in the evening.
of orphenadrine citrate are mainly due to the mild anti-cholinergic action of orphenadrine citrate and are usually associated with higher dosage. Dryness of the mouth is usually the first adverse effect to appear. When the daily dose is increased, possible adverse effects include tachycardia, palpitation, urinary hesitancy or retention, blurred vision, dilatation of pupils, increased ocular tension, weakness, nausea, vomiting, headache, dizziness, constipation, drowsiness, hypersensitivity reactions, pruritus, hallucinations, agitation, tremor, gastric irritation and rarely urticaria and other dermatoses. Infrequently, an elderly patient may experience some degree of mental confusion. These adverse reactions can usually be eliminated by reduction in dosage. Very rare cases of aplastic anemia associated with the use of orphenadrine tablets have been reported. No causal relationship has been established. To report SUSPECTED ADVERSE REACTIONS, contact Sandoz Inc. at 1-800-525-8747 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.
Contraindicated in patients with glaucoma, pyloric or duodenal obstruction, stenosing peptic ulcers, prostatic hypertrophy or obstruction of the bladder neck, cardio-spasm (megaesophagus) and myasthenia gravis. Contraindicated in patients who have demonstrated a previous hypersensitivity to the drug.
Same active ingredient — different manufacturer, form, price and FDA recall record. That last one is what our independent score measures.
| # | Drug | Rating | Type | Form | Generic? | Typical price | |
|---|---|---|---|---|---|---|---|
| 1 | Not yet rated | Prescription | Tablet | Generic | $0 | View → | |
| 2 | Not yet rated | Prescription | Tablet | Generic | $0 | View → |
Imprint codes, colour and shape from the FDA’s labelling data. Match the imprint on your pill — or search any imprint.
| Imprint | Strength | Colour | Shape | Maker |
|---|---|---|---|---|
| GA;473 | 50 mg / 770 mg / 60 mg | white | capsule | — |
| GA;473 | 50 mg / 770 mg / 60 mg | white | capsule | — |
| GA;473 | 50 mg / 770 mg / 60 mg | white, green | capsule | — |
| OAC472 | 25 mg / 385 mg / 30 mg | white | round | — |
| OAC472 | 25 mg / 385 mg / 30 mg | white | round | — |
| NL4 |
A combination is a different drug — different dosing, different warnings. It is listed here so you can find it, not so you can substitute it.
Sources: FDA openFDA drug label, National Drug Code Directory, and Enforcement (recall) database. This page reproduces public FDA data and is not medical advice. Dosing is set by your prescriber.
| 100 mg |
| white |
| round |
| — |
| NL4 | 100 mg | white | round | — |
|---|
| NL4 | 100 mg | white | round | — |
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| NL4 | 100 mg | white | round | — |
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