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Orphenadrine: uses, dosing, side effects & brands

Orphenadrine is a medicine sold in the U.S. under 2 brand and generic names. Below: what the FDA label says, every product that contains it, what the pills look like, and its recall record.

By the pharmaranks editorial teamReviewed against the FDA (openFDA label, NDC Directory & Enforcement) sourcesUpdated Jul 24, 2026How we research

Key facts

Available as
Tablet · Tablet, extended release · Injectable
Sold as
2 products — Disipal and Norflex
Prescription?
Prescription only
Generic available?
Not in our catalog
What the pharmacy pays
about $0.48 per ml — not your price

Every orphenadrine product we track (2)

Same active ingredient — different manufacturer, form, price and FDA recall record. That last one is what our independent score measures.

Orphenadrine products
#DrugRatingPharmacy pays
1Not yet rated$0View →
2Not yet rated$0View →

What orphenadrine pills look like

Imprint codes, colour and shape from the FDA’s labelling data. Match the imprint on your pill — or search any imprint.

Orphenadrine pill imprints
ImprintStrengthColourShape
NL4100 mgwhiteround
NL4100 mgwhiteround
NL4100 mgwhiteround
NL4100 mgwhiteround

Combination products containing orphenadrine

A combination is a different drug — different dosing, different warnings. It is listed here so you can find it, not so you can substitute it.

How long orphenadrine keeps

No orphenadrine label we read sets a separate limit for after opening, but they do specify how it must be stored — and the stability behind any date assumes those conditions.

What people report to the FDA about orphenadrine

The FDA Adverse Event Reporting System (FAERS) collects reports from patients and clinicians. It holds 912 reports naming orphenadrine, and the FDA flagged 74% of those reports as serious. The effects reported most often — leaving out reports about overdose, misuse or the condition being treated, which dominate the raw list for common medicines:

  • nausea68 reports
  • fatigue59 reports
  • anxiety54 reports
  • arthralgia53 reports
  • diarrhoea53 reports
  • headache53 reports
  • dizziness46 reports
  • fall44 reports

Read these as a signal, not a rate. A report does not mean orphenadrine caused the effect — anyone can file one, and many describe people taking several medicines for several conditions. Crucially there is no denominator: FAERS does not record how many people took the drug, so these counts cannot be turned into “X% of patients” — a bigger number often just means a more widely used or more talked-about drug. Duplicates exist, and publicity drives reporting. For what is actually established, read the FDA label.

Source: openFDA drug/event (FAERS), retrieved September 25, 2026.

Related calculators

Frequently asked questions

Can you take orphenadrine with other medicines?

It depends on the medicine. We check it against the FDA labels rather than guessing: our interaction checker searches each drug's own label for the other and quotes what it says, naming the section it came from. Run orphenadrine against whatever else you take — and remember that a label not naming a drug is not the same as that combination being safe.

What brand names is orphenadrine sold under?

We track 2 orphenadrine-containing products in the U.S.: Disipal and Norflex. They are the same active ingredient; they differ in form, manufacturer, price and FDA recall record.

What forms does orphenadrine come in?

Across the brands we track, orphenadrine is currently marketed as tablet, tablet, extended release and injectable, per the FDA's National Drug Code Directory. Each form is dosed differently — follow the label for the exact product you were prescribed.

Is there a generic orphenadrine?

We do not currently list a generic-labelled orphenadrine product. That does not always mean none exists — it means none appears under a generic name in the FDA data we track. Ask your pharmacist.

Cite this page
APA
pharmaranks. (2026, July 24). Orphenadrine: uses, dosing, side effects & brands. https://pharmaranks.com/drugs/orphenadrine
MLA
“Orphenadrine: uses, dosing, side effects & brands.” pharmaranks, 24 July 2026, https://pharmaranks.com/drugs/orphenadrine.

We summarise public FDA and NIH sources — for a clinical claim, cite the primary source we link to as well.

Sources: FDA openFDA drug label, National Drug Code Directory, and Enforcement (recall) database. This page reproduces public FDA data and is not medical advice. Dosing is set by your prescriber.

Read the full FDA label for orphenadrine on DailyMed (NIH) ↗.