Nevirapine Tablets USP is the brand name for nevirapine, a non-nucleoside reverse transcriptase inhibitor (NNRTI) with activity against Human Immunodeficiency Virus Type 1 (HIV-1). Nevirapine is structurally a member of the dipyridodiazepinone chemical class of compounds. The chemical name of nevirapine is 11-cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido [3,2-b:2',3'-e][1,4] diazepin-6-one. Nevirapine is a white to off-white crystalline powder with the molecular weight of 266.30 and the molecular formula C 15 H 14 N 4 O. Nevirapine has the following structural formula: Nevirapine Tablets, USP are for oral administration. Each tablet contains 200 mg of nevirapine and the inactive ingredients microcrystalline cellulose, lactose monohydrate, povidone, sodium starch glycolate, colloidal silicon dioxide and magnesium stearate str

What kind of drug is nevirapine?

The FDA classifies nevirapine as a human immunodeficiency virus 1 non-nucleoside analog reverse transcriptase inhibitor. If you are checking whether it is safe to combine with something else, the class is what matters — two drugs from the same class usually should not be stacked.

Can you take nevirapine with other medicines?

It depends on the medicine. We check it against the FDA labels rather than guessing: our interaction checker searches each drug's own label for the other and quotes what it says, naming the section it came from. Run nevirapine against whatever else you take — and remember that a label not naming a drug is not the same as that combination being safe.

What brand names is nevirapine sold under?

We track 3 nevirapine-containing products in the U.S.: Viramune, Viramune XR and Nevirapine. They are the same active ingredient; they differ in form, manufacturer, price and FDA recall record.

What forms does nevirapine come in?

Across the brands we track, nevirapine is currently marketed as suspension, tablet and tablet, extended release, per the FDA's National Drug Code Directory. Each form is dosed differently — follow the label for the exact product you were prescribed.

Is there a generic nevirapine?

Yes. Our catalog lists 1 generic nevirapine product alongside the brand versions. A generic has the same active ingredient and must meet the FDA's bioequivalence standard; it usually costs less. Ask your pharmacist which one your plan covers.

Nevirapine: uses, dosing, side effects & brands

Nevirapine is a human immunodeficiency virus 1 non-nucleoside analog reverse transcriptase inhibitor sold in the U.S. under 3 brand and generic names, for acquired immunodeficiency syndrome and hiv infections. Below: what the FDA label says, every product that contains it, what the pills look like, and its recall record.

By the pharmaranks editorial teamReviewed against the FDA (openFDA label, NDC Directory & Enforcement) sourcesHow we research

Key facts

Drug class: Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase Inhibitor
Treats: Acquired Immunodeficiency Syndrome and Hiv Infections
Available as: Suspension · Tablet · Tablet, extended release
Sold as: 3 products — Viramune, Viramune XR and Nevirapine
Prescription?: Prescription only
Generic available?: Yes
Typical price: about $5 for a 30-count supply
Boxed warning: Boxed warning

How nevirapine is dosed

From the FDA label for Viramune XR (application NDA201152). Other nevirapine products — different forms, different strengths — are dosed differently. Follow the label for the one you were prescribed.

2 DOSAGE & ADMINISTRATION • The 14-day lead-in period must be strictly followed; it has been demonstrated to reduce the frequency of rash. ( 2.4 , 5.2 ) • If any patient experiences rash during the 14-day lead-in period, do not increase dose until the rash has resolved. Do not continue the lead-in dosing regimen beyond 28 days. ( 2.4 ) • If dosing is interrupted for greater than 7 days, restart 14-day lead-in dosing. ( 2.4 ) Adults Pediatric Patients* (≥16 yrs) (≥15 days) First 14 days 200 mg once daily 150 mg/m 2 once daily After 14 days 200 mg twice daily 150 mg/m 2 twice daily *Total daily dose should not exceed 400 mg for any patient. 2.1 Adult Patients The recommended dose for nevirapine tablets is one 200 mg tablet daily for the first 14 days, followed by one 200 mg tablet twice daily, in combination with other antiretroviral agents. The 14-day lead-in period with nevirapine tablets 200 mg daily dosing must be strictly followed as the lead-in period has been observed to decrease the incidence of rash [see Dosage and Administration ( 2.4 ) and Warnings and Precautions ( 5.2 )]. If rash persists beyond the 14-day lead-in period, do not dose escalate to 200 mg twice daily. The 200 mg once-daily dosing regimen should not be continued beyond 28 days, at which point, an alternative regimen should be sought. For concomitantly administered antiretroviral therapy, the…

Nevirapine side effects

The most common adverse reaction is rash. In adults, the incidence of rash is 15% versus 6% with placebo, with Grade 3/4 rash occurring in 2% of subjects. ( 6.1 ) • In pediatric subjects the incidence of rash (all causality) was 21%. ( 6.1 ) To report SUSPECTED ADVERSE REACTIONS, contact Macleods Pharma USA, Inc. at 1-888-943-3210 or 1-855-926-3384 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch . 6.1 Clinical Trials Experience Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in clinical practice. Clinical Trial Experience in Adult Patients The most serious adverse reactions associated with nevirapine are hepatitis, hepatic failure, Stevens-Johnson syndrome, toxic epidermal necrolysis, and hypersensitivity reactions. Hepatitis/hepatic failure may be isolated or associated with signs of hypersensitivity which may include severe rash or rash accompanied by fever, general malaise, fatigue, muscle or joint aches, blisters, oral lesions, conjunctivitis, facial edema, eosinophilia, granulocytopenia, lymphadenopathy, or renal dysfunction [see Boxed Warning and Warnings and Precautions ( 5.1 , 5.2 )]. Hepatic Reaction In controlled clinical trials, symptomatic…

Every nevirapine product we track (3)

Same active ingredient — different manufacturer, form, price and FDA recall record. That last one is what our independent score measures.

Nevirapine products
#	Drug	Rating	Type	Form	Generic?	Typical price
1	Viramune	70/100	Prescription	Suspension	Generic	$5	View →
2	Viramune XR Boxed warning

What nevirapine pills look like

Imprint codes, colour and shape from the FDA’s labelling data. Match the imprint on your pill — or search any imprint.

Nevirapine pill imprints
Imprint	Strength	Colour	Shape	Maker
N;2	200 mg	white	oval	—
I;11	200 mg	white	oval	—
M;N400	400 mg	white	oval	—
C11	400 mg	yellow	oval	—

Combination products containing nevirapine

A combination is a different drug — different dosing, different warnings. It is listed here so you can find it, not so you can substitute it.

Lamivudine; Nevirapine; Zidovudine

Frequently asked questions

What is nevirapine?: Nevirapine Tablets USP is the brand name for nevirapine, a non-nucleoside reverse transcriptase inhibitor (NNRTI) with activity against Human Immunodeficiency Virus Type 1 (HIV-1). Nevirapine is structurally a member of the dipyridodiazepinone chemical class of compounds. The chemical name of nevirapine is 11-cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido [3,2-b:2',3'-e][1,4] diazepin-6-one. Nevirapine is a white to off-white crystalline powder with the molecular weight of 266.30 and the molecular formula C 15 H 14 N 4 O. Nevirapine has the following structural formula: Nevirapine Tablets, USP are for oral administration. Each tablet contains 200 mg of nevirapine and the inactive ingredients microcrystalline cellulose, lactose monohydrate, povidone, sodium starch glycolate, colloidal silicon dioxide and magnesium stearate str
What kind of drug is nevirapine?: The FDA classifies nevirapine as a human immunodeficiency virus 1 non-nucleoside analog reverse transcriptase inhibitor. If you are checking whether it is safe to combine with something else, the class is what matters — two drugs from the same class usually should not be stacked.
Can you take nevirapine with other medicines?: It depends on the medicine. We check it against the FDA labels rather than guessing: our interaction checker searches each drug's own label for the other and quotes what it says, naming the section it came from. Run nevirapine against whatever else you take — and remember that a label not naming a drug is not the same as that combination being safe.
What brand names is nevirapine sold under?: We track 3 nevirapine-containing products in the U.S.: Viramune, Viramune XR and Nevirapine. They are the same active ingredient; they differ in form, manufacturer, price and FDA recall record.
What forms does nevirapine come in?: Across the brands we track, nevirapine is currently marketed as suspension, tablet and tablet, extended release, per the FDA's National Drug Code Directory. Each form is dosed differently — follow the label for the exact product you were prescribed.

Sources: FDA openFDA drug label, National Drug Code Directory, and Enforcement (recall) database. This page reproduces public FDA data and is not medical advice. Dosing is set by your prescriber.