Question 1

What is lisdexamfetamine dimesylate?

Accepted Answer

ARYNTA (lisdexamfetamine dimesylate), is a CNS stimulant. The chemical designation for lisdexamfetamine dimesylate is (2S)-2,6-diamino-N-[(1S)-1-methyl-2-phenylethyl] hexanamide dimethanesulfonate. The molecular formula is C 15 H 25 N 3 O∙(CH 4 O 3 S) 2 , which corresponds to a molecular weight of 455.60. The chemical structure is: Lisdexamfetamine dimesylate is a white to off-white powder that is soluble in water (792 mg/mL). The pH is 4.24. The pKa values are 10.21 and 15.89. ARYNTA oral solution is a clear colorless solution, contains 10 mg/mL of lisdexamfetamine dimesylate (equivalent to 5.8 mg of lisdexamfetamine). Inactive ingredients: dibasic sodium phosphate dihydrate, methylparaben sodium, monobasic sodium phosphate dihydrate, propylparaben sodium, propylene glycol, saccharin sodium, hydrochloric acid, sodium hydroxide and purified water. Lisdex Structure

Question 2

What kind of drug is lisdexamfetamine dimesylate?

Accepted Answer

The FDA classifies lisdexamfetamine dimesylate as a central nervous system stimulant. CNS stimulants raise the levels of the brain's signaling chemicals dopamine and norepinephrine, either by releasing more of them or by blocking their reuptake. This heightened activity in attention and arousal circuits increases alertness, energy, and focus. If you are checking whether it is safe to combine with something else, the class is what matters — two drugs from the same class usually should not be stacked.

Question 3

How long does lisdexamfetamine dimesylate stay in your system?

Accepted Answer

The elimination half-life of lisdexamfetamine dimesylate is less than 1 hour (parent drug) — that is how long the body takes to clear half of a dose. Lisdexamfetamine is an inactive prodrug: the parent's own elimination half-life is under 1 hour and it is essentially undetectable in blood by 8 hours. The clinically meaningful effect comes from its active metabolite, dextroamphetamine, which has a much longer elimination half-life of about 10 to 11 hours in healthy adults (about 8.6 to 9.5 hours in children 6 to 12). Half-life is not the same as how long a drug test can detect the drug, and it varies with age, kidney and liver function.

Question 4

Can you take lisdexamfetamine dimesylate with other medicines?

Accepted Answer

It depends on the medicine. We check it against the FDA labels rather than guessing: our interaction checker searches each drug's own label for the other and quotes what it says, naming the section it came from. Run lisdexamfetamine dimesylate against whatever else you take — and remember that a label not naming a drug is not the same as that combination being safe.

Question 5

What brand names is lisdexamfetamine dimesylate sold under?

Accepted Answer

We track 3 lisdexamfetamine dimesylate-containing products in the U.S.: Arynta, Lisdexamfetamine Dimesylate and Vyvanse. They are the same active ingredient; they differ in form, manufacturer, price and FDA recall record.

Question 6

What forms does lisdexamfetamine dimesylate come in?

Accepted Answer

Across the brands we track, lisdexamfetamine dimesylate is currently marketed as solution, capsule and tablet, chewable, per the FDA's National Drug Code Directory. Each form is dosed differently — follow the label for the exact product you were prescribed.

Question 7

Is there a generic lisdexamfetamine dimesylate?

Accepted Answer

Yes. Our catalog lists 1 generic lisdexamfetamine dimesylate product alongside the brand versions. A generic has the same active ingredient and must meet the FDA's bioequivalence standard; it usually costs less. Ask your pharmacist which one your plan covers.

Question 8

Has lisdexamfetamine dimesylate been recalled?

Accepted Answer

The FDA's Enforcement database lists at least 5 recall records whose product description mentions lisdexamfetamine dimesylate. The most recent: Lisdexamfetamine Dimesylate Capsules (Oct 28, 2025). A recall applies to specific lots, not to the drug as a whole — check the record for the affected lot numbers.

#	Drug	Rating	Type	Form	Generic?	Typical price
1	Arynta Boxed warning	72/100	Prescription	Solution	—	—	View →
2	Lisdexamfetamine Dimesylate

Imprint	Strength	Colour	Shape	Maker
E0550;10mg	10 mg	pink	capsule	—
E0551;20mg	20 mg	white	capsule	—
E0552;30mg	30 mg	white, orange	capsule	—
E0553;40mg	40 mg	white, turquoise	capsule	—
E0554;50mg	50 mg	white, blue	capsule	—
E0555;60mg

Lisdexamfetamine Dimesylate: uses, dosing, side effects & brands

Key facts

How lisdexamfetamine dimesylate is dosed

Lisdexamfetamine Dimesylate side effects

Every lisdexamfetamine dimesylate product we track (3)

What lisdexamfetamine dimesylate pills look like

Lisdexamfetamine Dimesylate recalls

How long lisdexamfetamine dimesylate stays in your system

Frequently asked questions

Who shouldn’t take lisdexamfetamine dimesylate

Lisdexamfetamine Dimesylate drug interactions