Carvedilol is a nonselective β-adrenergic blocking agent with α1-blocking activity. It is (±)-1-(Carbazol-4-yloxy)-3-[[2-(o-methoxyphenoxy)ethyl]amino]-2-propanol. Carvedilol is a racemic mixture with the following structure: COREG is a white, oval, film-coated tablet containing 3.125 mg, 6.25 mg, 12.5 mg, or 25 mg of carvedilol. The 6.25-mg, 12.5-mg, and 25-mg tablets are TILTAB tablets. Inactive ingredients consist of colloidal silicon dioxide, crospovidone, hypromellose, lactose, magnesium stearate, polyethylene glycol, polysorbate 80, povidone, sucrose, and titanium dioxide. Carvedilol is a white to off-white powder with a molecular weight of 406.5 and a molecular formula of C24H26N2O4. It is freely soluble in dimethylsulfoxide; soluble in methylene chloride and methanol; sparingly soluble in 95% ethanol and isopropanol; slightly soluble in ethyl ether; and practically insoluble in water, gastric fluid (simulated, TS, pH 1.1), and intestinal fluid (simulated, TS without pancreatin, pH 7.5). Chemical Structure

What kind of drug is carvedilol?

The FDA classifies carvedilol as an alpha-adrenergic blocker. Alpha-adrenergic blockers block the alpha-1 receptors that adrenaline-like signals use to tighten muscle in blood vessels and the prostate. This relaxes those muscles, lowering blood pressure and easing urine flow in men with an enlarged prostate. If you are checking whether it is safe to combine with something else, the class is what matters — two drugs from the same class usually should not be stacked.

Can you take carvedilol with other medicines?

It depends on the medicine. We check it against the FDA labels rather than guessing: our interaction checker searches each drug's own label for the other and quotes what it says, naming the section it came from. Run carvedilol against whatever else you take — and remember that a label not naming a drug is not the same as that combination being safe.

What brand names is carvedilol sold under?

We track 2 carvedilol-containing products in the U.S.: Coreg and Coreg CR. They are the same active ingredient; they differ in form, manufacturer, price and FDA recall record.

What forms does carvedilol come in?

Across the brands we track, carvedilol is currently marketed as tablet and capsule, extended release, per the FDA's National Drug Code Directory. Each form is dosed differently — follow the label for the exact product you were prescribed.

Is there a generic carvedilol?

We do not currently list a generic-labelled carvedilol product. That does not always mean none exists — it means none appears under a generic name in the FDA data we track. Ask your pharmacist.

Has carvedilol been recalled?

The FDA's Enforcement database lists at least 5 recall records whose product description mentions carvedilol. The most recent: Carvedilol Tablets USP (Aug 20, 2025). A recall applies to specific lots, not to the drug as a whole — check the record for the affected lot numbers.

Carvedilol: uses, dosing, side effects & brands

Carvedilol is an alpha-adrenergic blocker sold in the U.S. under 2 brand and generic names, for angina pectoris, heart failure and hypertension. Below: what the FDA label says, every product that contains it, what the pills look like, and its recall record.

By the pharmaranks editorial teamReviewed against the FDA (openFDA label, NDC Directory & Enforcement) sourcesHow we research

Key facts

Drug class: Alpha-Adrenergic Blocker
Treats: Angina Pectoris, Heart Failure and Hypertension
Available as: Tablet · Capsule, extended release
Sold as: 2 products — Coreg and Coreg CR
Prescription?: Prescription only
Generic available?: Not in our catalog
Typical price: about $1 for a 30-count supply

How carvedilol is dosed

From the FDA label for Coreg (application NDA020297). Other carvedilol products — different forms, different strengths — are dosed differently. Follow the label for the one you were prescribed.

COREG should be taken with food to slow the rate of absorption and reduce the incidence of orthostatic effects. Take with food. Individualize dosage and monitor during up-titration. ( 2 ) Heart failure: Start at 3.125 mg twice daily and increase to 6.25, 12.5, and then 25mg twice daily over intervals of at least 2 weeks. Maintain lower doses if higher doses are not tolerated. ( 2.1 ) Left ventricular dysfunction following myocardial infarction. Start at 6.25 mg twice daily and increase to 12.5 mg then 25 mg twice daily after intervals of 3 to 10 days. A lower starting dose or slower titration may be used. ( 2.2 ) Hypertension: Start at 6.25 mg twice daily and increase if needed for blood pressure control to 12.5 mg and then 25 mg twice daily over intervals of 1 to 2 weeks. ( 2.3 ) 2.1 Heart Failure DOSAGE MUST BE INDIVIDUALIZED AND CLOSELY MONITORED BY A PHYSICIAN DURING UP-TITRATION. Prior to initiation of COREG, it is recommended that fluid retention be minimized. The recommended starting dose of COREG is 3.125 mg twice daily for 2 weeks. If tolerated, patients may have their dose increased to 6.25, 12.5, and 25 mg twice daily over successive intervals of at least 2 weeks. Patients should be maintained on lower doses if higher doses are not tolerated. A maximum dose of 50 mg twice daily has been administered to patients with mild-to-moderate heart…

Carvedilol side effects

Most common adverse events ( 6.1 ): Heart failure and left ventricular dysfunction following myocardial infarction (≤10%): Dizziness, fatigue, hypotension, diarrhea, hyperglycemia, asthenia, bradycardia, weight increase. Hypertension (≥5%): Dizziness. To report SUSPECTED ADVERSE REACTIONS, contact Waylis Therapeutics LLC at 1-844-200-7910 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch. 6.1 Clinical Studies Experience Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared with rates in the clinical trials of another drug and may not reflect the rates observed in practice. COREG has been evaluated for safety in subjects with heart failure (mild, moderate, and severe), in subjects with left ventricular dysfunction following myocardial infarction and in hypertensive subjects The observed adverse event profile was consistent with the pharmacology of the drug and the health status of the subjects in the clinical trials. Adverse events reported for each of these patient populations are provided below. Excluded are adverse events considered too general to be informative, and those not reasonably associated with the use of the drug because they were associated with the condition being treated or are very common in the treated population. Rates of adverse events were generally…

Every carvedilol product we track (2)

Same active ingredient — different manufacturer, form, price and FDA recall record. That last one is what our independent score measures.

Carvedilol products
#	Drug	Rating	Type	Form	Generic?	Typical price
1	Coreg	Not yet rated	Prescription	Tablet	Generic	$1	View →
2	Coreg CR	Not yet rated	Prescription	Capsule	Generic	$1	View →

What carvedilol pills look like

Imprint codes, colour and shape from the FDA’s labelling data. Match the imprint on your pill — or search any imprint.

Carvedilol pill imprints
Imprint	Strength	Colour	Shape	Maker
Mutual;899	10 mg	white	capsule	—
Mutual;900	20 mg	green	capsule	—
H31	10 mg	white, green	capsule	—
H32	20 mg	white, orange	capsule	—
H33	40 mg	orange, green	capsule	—
H34	80 mg

Carvedilol recalls

From the FDA Enforcement database. A recall covers specific lots — not the drug as a whole.

Frequently asked questions

What is carvedilol?: Carvedilol is a nonselective β-adrenergic blocking agent with α1-blocking activity. It is (±)-1-(Carbazol-4-yloxy)-3-[[2-(o-methoxyphenoxy)ethyl]amino]-2-propanol. Carvedilol is a racemic mixture with the following structure: COREG is a white, oval, film-coated tablet containing 3.125 mg, 6.25 mg, 12.5 mg, or 25 mg of carvedilol. The 6.25-mg, 12.5-mg, and 25-mg tablets are TILTAB tablets. Inactive ingredients consist of colloidal silicon dioxide, crospovidone, hypromellose, lactose, magnesium stearate, polyethylene glycol, polysorbate 80, povidone, sucrose, and titanium dioxide. Carvedilol is a white to off-white powder with a molecular weight of 406.5 and a molecular formula of C24H26N2O4. It is freely soluble in dimethylsulfoxide; soluble in methylene chloride and methanol; sparingly soluble in 95% ethanol and isopropanol; slightly soluble in ethyl ether; and practically insoluble in water, gastric fluid (simulated, TS, pH 1.1), and intestinal fluid (simulated, TS without pancreatin, pH 7.5). Chemical Structure
What kind of drug is carvedilol?: The FDA classifies carvedilol as an alpha-adrenergic blocker. Alpha-adrenergic blockers block the alpha-1 receptors that adrenaline-like signals use to tighten muscle in blood vessels and the prostate. This relaxes those muscles, lowering blood pressure and easing urine flow in men with an enlarged prostate. If you are checking whether it is safe to combine with something else, the class is what matters — two drugs from the same class usually should not be stacked.
Can you take carvedilol with other medicines?: It depends on the medicine. We check it against the FDA labels rather than guessing: our interaction checker searches each drug's own label for the other and quotes what it says, naming the section it came from. Run carvedilol against whatever else you take — and remember that a label not naming a drug is not the same as that combination being safe.
What brand names is carvedilol sold under?: We track 2 carvedilol-containing products in the U.S.: Coreg and Coreg CR. They are the same active ingredient; they differ in form, manufacturer, price and FDA recall record.

Sources: FDA openFDA drug label, National Drug Code Directory, and Enforcement (recall) database. This page reproduces public FDA data and is not medical advice. Dosing is set by your prescriber.