Question 1

What is cabozantinib s-?

Accepted Answer

CABOMETYX is the ( S )-malate salt of cabozantinib, a kinase inhibitor. Cabozantinib ( S )-malate is described chemically as N -(4-(6,7-dimethoxyquinolin-4-yloxy)phenyl)- N' -(4-fluorophenyl)cyclopropane-1,1-dicarboxamide, (2 S )-hydroxybutanedioate. The molecular formula is C 28 H 24 FN 3 O 5 •C 4 H 6 O 5 and the molecular weight is 635.6 Daltons as malate salt. The chemical structure of cabozantinib ( S )-malate salt is: Cabozantinib ( S )-malate salt is a white to off-white solid that is practically insoluble in aqueous media. CABOMETYX (cabozantinib) tablets for oral use are supplied as film-coated tablets containing 20 mg, 40 mg, or 60 mg of cabozantinib, which is equivalent to 25 mg, 51 mg, or 76 mg of cabozantinib ( S )-malate, respectively. CABOMETYX also contains the following inactive ingredients: microcrystalline cellulose, lactose anhydrous, hydroxypropyl cellulose, croscarmellose sodium, colloidal silicon dioxide, and magnesium stearate. The film coating contains hypromellose, titanium dioxide, triacetin, and iron oxide yellow.

Question 2

What kind of drug is cabozantinib s-?

Accepted Answer

The FDA classifies cabozantinib s- as a kinase inhibitor. Kinase inhibitors block protein kinases, the enzymes that relay 'grow and divide' signals inside cells. By shutting down the overactive kinase signals that a tumor depends on, they help slow or stop cancer cells from multiplying. If you are checking whether it is safe to combine with something else, the class is what matters — two drugs from the same class usually should not be stacked.

Question 3

Can you take cabozantinib s- with other medicines?

Accepted Answer

It depends on the medicine. We check it against the FDA labels rather than guessing: our interaction checker searches each drug's own label for the other and quotes what it says, naming the section it came from. Run cabozantinib s- against whatever else you take — and remember that a label not naming a drug is not the same as that combination being safe.

Question 4

What brand names is cabozantinib s- sold under?

Accepted Answer

We track 2 cabozantinib s--containing products in the U.S.: Cabometyx and Cometriq. They are the same active ingredient; they differ in form, manufacturer, price and FDA recall record.

Question 5

What forms does cabozantinib s- come in?

Accepted Answer

Across the brands we track, cabozantinib s- is currently marketed as tablet, capsule and kit, per the FDA's National Drug Code Directory. Each form is dosed differently — follow the label for the exact product you were prescribed.

Question 6

Is there a generic cabozantinib s-?

Accepted Answer

We do not currently list a generic-labelled cabozantinib s- product. That does not always mean none exists — it means none appears under a generic name in the FDA data we track. Ask your pharmacist.

#	Drug	Rating	Type	Form	Generic?	Typical price
1	Cabometyx	Not yet rated	Prescription	Tablet	—	—	View →
2	Cometriq	Not yet rated	Prescription	Capsule	—	—	View →

Cabozantinib S-: uses, dosing, side effects & brands

Key facts

How cabozantinib s- is dosed

Cabozantinib S- side effects

Every cabozantinib s- product we track (2)

Frequently asked questions

Who shouldn’t take cabozantinib s-

Cabozantinib S- drug interactions