Generally yes — CoQ10 is commonly taken alongside statins and isn't flagged as a dangerous combination, but it's not a proven fix for statin muscle pain, so check with your pharmacist or doctor first.
CoQ10 is one of the most common supplements people add while taking a statin, often in the hope of easing statin-related muscle aches. According to NCCIH (part of the NIH), no serious side effects of CoQ10 have been reported — only mild ones such as insomnia or digestive upset — and it is not flagged as a dangerous statin combination. Importantly, though, NCCIH also states that the overall scientific evidence does not support the idea that CoQ10 can reduce muscle pain caused by statins. So CoQ10 is best viewed as low-risk rather than proven-helpful, and it is not a substitute for your statin. (You may also see claims that statins lower the body's CoQ10 levels; that is a commonly cited rationale, but it is not confirmed by the NCCIH source here.)
Tell your doctor or pharmacist before adding CoQ10, especially if you take the blood thinner warfarin or insulin for diabetes, since NCCIH notes CoQ10 may interact with both (and it may not be compatible with some cancer treatments). CoQ10 is not a reason to stop or skip your statin — do not stop your statin on your own. Most importantly, do not treat unexplained muscle pain as a supplement problem: NHS guidance says to stop the statin and call a doctor (or 111 in the UK) straight away if you get unexplained muscle pain, tenderness, weakness, or cramps, as these can rarely signal serious muscle breakdown and kidney damage. If your statin is causing side effects, talk to your doctor first — they may adjust the dose or switch the drug.
This is general reference, not medical advice, and not a guarantee of safety. Interactions depend on your doses, health conditions, and other medicines. Always confirm with your pharmacist or doctor before combining products, and follow the dosing on each label.